Adamts-5-IN-2
TL;DR: Adamts-5-IN-2 (CAS 294648-66-1) is a chemical compound with molecular formula C17H15N3OS and molecular weight 309.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-ethyl-5'-phenylspiro[1H-indole-3,2'-3H-1,3,4-thiadiazole]-2-one
Also Known As: ADAMTS-5-IN-2, thiadiazole derivative, 11, BAS 01967821, VU0475961-1, A0325/0014890
| Molecular Formula | C17H15N3OS |
|---|---|
| Molecular Weight | 309.09 g/mol |
| LogP | 3.0521 |
| Topological Polar Surface Area | 53.49 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 309.0936 |
| Heavy Atoms | 22 |
| Complexity | 787.746 |
Chemical Identifiers
| CAS Number | 294648-66-1 |
|---|---|
| SMILES | CCC1=CC2=C(C=C1)NC(=O)C23NN=C(S3)C4=CC=CC=C4 |
Product Overview
Adamts-5-IN-2 (CAS 294648-66-1), with molecular formula C17H15N3OS and molecular weight 309.09 g/mol. IUPAC: 5-ethyl-5'-phenylspiro[1H-indole-3,2'-3H-1,3,4-thiadiazole]-2-one.
Chemical Property Profile of Adamts-5-IN-2
Property Insights of Adamts-5-IN-2
The XLogP value of 3.0521 indicates that Adamts-5-IN-2 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 53.49 Ų, Adamts-5-IN-2 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Adamts-5-IN-2 has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Adamts-5-IN-2?
The CAS number of Adamts-5-IN-2 is 294648-66-1.
What is the molecular formula of Adamts-5-IN-2?
The molecular formula of Adamts-5-IN-2 is C17H15N3OS.
What is the molecular weight of Adamts-5-IN-2?
The molecular weight of Adamts-5-IN-2 is 309.09 g/mol.
Where can I buy Adamts-5-IN-2?
You can request a quote for Adamts-5-IN-2 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Adamts-5-IN-2?
Yes, KEHONG BIO provides custom synthesis services for Adamts-5-IN-2 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.