10-Oxo Naloxone
TL;DR: 10-Oxo Naloxone (CAS 294175-43-2) is a chemical compound with molecular formula C19H19NO5 and molecular weight 341.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4S,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7a-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7,13-dione
Also Known As: 10-Oxo Naloxone, 10-Keto Naloxone, 10-Oxo Naloxone (1 mg/ml in Acetonitrile), 10-Oxo Naloxone (1.0mg/ml in Acetonitrile), J1.451.181D
| Molecular Formula | C19H19NO5 |
|---|---|
| Molecular Weight | 341.13 g/mol |
| LogP | 0.9416 |
| Topological Polar Surface Area | 87.07 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 341.1263 |
| Heavy Atoms | 25 |
| Complexity | 848.46136 |
Chemical Identifiers
| CAS Number | 294175-43-2 |
|---|---|
| SMILES | C=CCN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1C(=O)C5=C3C(=C(C=C5)O)O4)O |
Product Overview
10-Oxo Naloxone (CAS 294175-43-2), with molecular formula C19H19NO5 and molecular weight 341.13 g/mol. IUPAC: (4S,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7a-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7,13-dione.
Chemical Property Profile of 10-Oxo Naloxone
Property Insights of 10-Oxo Naloxone
The XLogP value of 0.9416 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 10-Oxo Naloxone. The TPSA of 87.07 Ų falls within the moderate polarity range, balancing permeability and solubility for 10-Oxo Naloxone. Following Lipinski's Rule of Five, 10-Oxo Naloxone has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 10-Oxo Naloxone?
The CAS number of 10-Oxo Naloxone is 294175-43-2.
What is the molecular formula of 10-Oxo Naloxone?
The molecular formula of 10-Oxo Naloxone is C19H19NO5.
What is the molecular weight of 10-Oxo Naloxone?
The molecular weight of 10-Oxo Naloxone is 341.13 g/mol.
Where can I buy 10-Oxo Naloxone?
You can request a quote for 10-Oxo Naloxone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 10-Oxo Naloxone?
Yes, KEHONG BIO provides custom synthesis services for 10-Oxo Naloxone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.