7-Phenyliminomethylcamptothecin
TL;DR: 7-Phenyliminomethylcamptothecin (CAS 292620-93-0) is a chemical compound with molecular formula C27H21N3O4 and molecular weight 451.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(19S)-19-ethyl-19-hydroxy-10-(phenyliminomethyl)-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
Also Known As: 7-Phenyliminomethylcamptothecin, 1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-11-((phenylimino)methyl)-, (4S)-
| Molecular Formula | C27H21N3O4 |
|---|---|
| Molecular Weight | 451.15 g/mol |
| LogP | 3.8302 |
| Topological Polar Surface Area | 93.78 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 451.1532 |
| Heavy Atoms | 34 |
| Complexity | 1572.8533 |
Chemical Identifiers
| CAS Number | 292620-93-0 |
|---|---|
| SMILES | CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C5=CC=CC=C5N=C4C3=C2)C=NC6=CC=CC=C6)O |
Product Overview
7-Phenyliminomethylcamptothecin (CAS 292620-93-0), with molecular formula C27H21N3O4 and molecular weight 451.15 g/mol. IUPAC: (19S)-19-ethyl-19-hydroxy-10-(phenyliminomethyl)-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione.
Chemical Property Profile of 7-Phenyliminomethylcamptothecin
Property Insights of 7-Phenyliminomethylcamptothecin
The XLogP value of 3.8302 indicates that 7-Phenyliminomethylcamptothecin is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 93.78 Ų falls within the moderate polarity range, balancing permeability and solubility for 7-Phenyliminomethylcamptothecin. Following Lipinski's Rule of Five, 7-Phenyliminomethylcamptothecin has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-Phenyliminomethylcamptothecin?
The CAS number of 7-Phenyliminomethylcamptothecin is 292620-93-0.
What is the molecular formula of 7-Phenyliminomethylcamptothecin?
The molecular formula of 7-Phenyliminomethylcamptothecin is C27H21N3O4.
What is the molecular weight of 7-Phenyliminomethylcamptothecin?
The molecular weight of 7-Phenyliminomethylcamptothecin is 451.15 g/mol.
Where can I buy 7-Phenyliminomethylcamptothecin?
You can request a quote for 7-Phenyliminomethylcamptothecin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-Phenyliminomethylcamptothecin?
Yes, KEHONG BIO provides custom synthesis services for 7-Phenyliminomethylcamptothecin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.