7-tert-Butoxyiminomethylcamptothecin
TL;DR: 7-tert-Butoxyiminomethylcamptothecin (CAS 292618-32-7) is a chemical compound with molecular formula C25H25N3O5 and molecular weight 447.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(19S)-19-ethyl-19-hydroxy-10-[(2-methylpropan-2-yl)oxyiminomethyl]-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
Also Known As: 7-tert-butyl-IMC, 7-tert-Butoxyiminomethylcamptothecin, (19S)-19-ethyl-19-hydroxy-10-[(2-methylpropan-2-yl)oxyiminomethyl]-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione, (4S)-11-[(tert-Butoxyimino)methyl]-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-11-carboxaldehyde, 4-ethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-, 11-(O-(1,1-dimethylethyl)oxime), (4S)-
| Molecular Formula | C25H25N3O5 |
|---|---|
| Molecular Weight | 447.18 g/mol |
| LogP | 2.0 |
| Topological Polar Surface Area | 101.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 4 |
| Exact Mass | 447.1794 |
| Heavy Atoms | 33 |
| Complexity | 948.0 |
Chemical Identifiers
| CAS Number | 292618-32-7 |
|---|---|
| SMILES | CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C5=CC=CC=C5N=C4C3=C2)C=NOC(C)(C)C)O |
| InChIKey | UIVFUQKYVFCEKJ-VWLOTQADSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
7-tert-Butoxyiminomethylcamptothecin (CAS 292618-32-7), with molecular formula C25H25N3O5 and molecular weight 447.18 g/mol. IUPAC: (19S)-19-ethyl-19-hydroxy-10-[(2-methylpropan-2-yl)oxyiminomethyl]-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione.
Chemical Property Profile of 7-tert-Butoxyiminomethylcamptothecin
Property Insights of 7-tert-Butoxyiminomethylcamptothecin
The XLogP value of 2.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 7-tert-Butoxyiminomethylcamptothecin. The TPSA of 101.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 7-tert-Butoxyiminomethylcamptothecin. Following Lipinski's Rule of Five, 7-tert-Butoxyiminomethylcamptothecin has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-tert-Butoxyiminomethylcamptothecin?
The CAS number of 7-tert-Butoxyiminomethylcamptothecin is 292618-32-7.
What is the molecular formula of 7-tert-Butoxyiminomethylcamptothecin?
The molecular formula of 7-tert-Butoxyiminomethylcamptothecin is C25H25N3O5.
What is the molecular weight of 7-tert-Butoxyiminomethylcamptothecin?
The molecular weight of 7-tert-Butoxyiminomethylcamptothecin is 447.18 g/mol.
Where can I buy 7-tert-Butoxyiminomethylcamptothecin?
You can request a quote for 7-tert-Butoxyiminomethylcamptothecin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-tert-Butoxyiminomethylcamptothecin?
Yes, KEHONG BIO provides custom synthesis services for 7-tert-Butoxyiminomethylcamptothecin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.