2'-Deoxy-2'-fluorothymidine
TL;DR: 2'-Deoxy-2'-fluorothymidine (CAS 2923-73-1) is a chemical compound with molecular formula C10H13FN2O5 and molecular weight 260.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Also Known As: Clevudine, 2'-Fluorothymidine, Monomyristin, 2'-Deoxy-2'-fluorothymidine, L-FMAU; L FMAU; LFMAU
| Molecular Formula | C10H13FN2O5 |
|---|---|
| Molecular Weight | 260.08 g/mol |
| LogP | -0.9 |
| Topological Polar Surface Area | 99.1 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 260.08084 |
| Heavy Atoms | 18 |
| Complexity | 413.0 |
Chemical Identifiers
| CAS Number | 2923-73-1 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)F |
| InChIKey | GBBJCSTXCAQSSJ-UHFFFAOYSA-N |
Product Overview
2'-Deoxy-2'-fluorothymidine (CAS 2923-73-1), with molecular formula C10H13FN2O5 and molecular weight 260.08 g/mol. IUPAC: 1-[3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione.
Chemical Property Profile of 2'-Deoxy-2'-fluorothymidine
Property Insights of 2'-Deoxy-2'-fluorothymidine
The XLogP value of -0.9 indicates that 2'-Deoxy-2'-fluorothymidine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 99.1 Ų falls within the moderate polarity range, balancing permeability and solubility for 2'-Deoxy-2'-fluorothymidine. Following Lipinski's Rule of Five, 2'-Deoxy-2'-fluorothymidine has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2'-Deoxy-2'-fluorothymidine?
The CAS number of 2'-Deoxy-2'-fluorothymidine is 2923-73-1.
What is the molecular formula of 2'-Deoxy-2'-fluorothymidine?
The molecular formula of 2'-Deoxy-2'-fluorothymidine is C10H13FN2O5.
What is the molecular weight of 2'-Deoxy-2'-fluorothymidine?
The molecular weight of 2'-Deoxy-2'-fluorothymidine is 260.08 g/mol.
Where can I buy 2'-Deoxy-2'-fluorothymidine?
You can request a quote for 2'-Deoxy-2'-fluorothymidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2'-Deoxy-2'-fluorothymidine?
Yes, KEHONG BIO provides custom synthesis services for 2'-Deoxy-2'-fluorothymidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.