![(2E)-3-(4-chlorophenyl)-N-[5-(4-fluorobenzyl)-1,3-thiazol-2-yl]-2-propenamide structure](/static/products/2920/292057-18-2.webp)
(2E)-3-(4-chlorophenyl)-N-[5-(4-fluorobenzyl)-1,3-thiazol-2-yl]-2-propenamide
TL;DR: (2E)-3-(4-chlorophenyl)-N-[5-(4-fluorobenzyl)-1,3-thiazol-2-yl]-2-propenamide (CAS 292057-18-2) is a chemical compound with molecular formula C19H14ClFN2OS and molecular weight 372.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-(4-chlorophenyl)-N-[5-[(4-fluorophenyl)methyl]-1,3-thiazol-2-yl]prop-2-enamide
Also Known As: (E)-3-(4-chlorophenyl)-N-(5-(4-fluorobenzyl)thiazol-2-yl)acrylamide, (2E)-3-(4-chlorophenyl)-N-[5-(4-fluorobenzyl)-1,3-thiazol-2-yl]-2-propenamide, (2E)-3-(4-chlorophenyl)-N-[5-(4-fluorobenzyl)-1,3-thiazol-2-yl]prop-2-enamide, (2E)-3-(4-chlorophenyl)-N-{5-[(4-fluorophenyl)methyl](1,3-thiazol-2-yl)}prop-2 -enamide, (E)-3-(4-chlorophenyl)-N-[5-[(4-fluorophenyl)methyl]-1,3-thiazol-2-yl]prop-2-enamide
| Molecular Formula | C19H14ClFN2OS |
|---|---|
| Molecular Weight | 372.05 g/mol |
| LogP | 5.1783 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 372.04993 |
| Heavy Atoms | 25 |
| Complexity | 888.54736 |
Chemical Identifiers
| CAS Number | 292057-18-2 |
|---|---|
| SMILES | C1=CC(=CC=C1CC2=CN=C(S2)NC(=O)/C=C/C3=CC=C(C=C3)Cl)F |
Product Overview
(2E)-3-(4-chlorophenyl)-N-[5-(4-fluorobenzyl)-1,3-thiazol-2-yl]-2-propenamide (CAS 292057-18-2), with molecular formula C19H14ClFN2OS and molecular weight 372.05 g/mol. IUPAC: (E)-3-(4-chlorophenyl)-N-[5-[(4-fluorophenyl)methyl]-1,3-thiazol-2-yl]prop-2-enamide.
Chemical Property Profile of (2E)-3-(4-chlorophenyl)-N-[5-(4-fluorobenzyl)-1,3-thiazol-2-yl]-2-propenamide
Property Insights of (2E)-3-(4-chlorophenyl)-N-[5-(4-fluorobenzyl)-1,3-thiazol-2-yl]-2-propenamide
The XLogP value of 5.1783 indicates that (2E)-3-(4-chlorophenyl)-N-[5-(4-fluorobenzyl)-1,3-thiazol-2-yl]-2-propenamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, (2E)-3-(4-chlorophenyl)-N-[5-(4-fluorobenzyl)-1,3-thiazol-2-yl]-2-propenamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (2E)-3-(4-chlorophenyl)-N-[5-(4-fluorobenzyl)-1,3-thiazol-2-yl]-2-propenamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2E)-3-(4-chlorophenyl)-N-[5-(4-fluorobenzyl)-1,3-thiazol-2-yl]-2-propenamide?
The CAS number of (2E)-3-(4-chlorophenyl)-N-[5-(4-fluorobenzyl)-1,3-thiazol-2-yl]-2-propenamide is 292057-18-2.
What is the molecular formula of (2E)-3-(4-chlorophenyl)-N-[5-(4-fluorobenzyl)-1,3-thiazol-2-yl]-2-propenamide?
The molecular formula of (2E)-3-(4-chlorophenyl)-N-[5-(4-fluorobenzyl)-1,3-thiazol-2-yl]-2-propenamide is C19H14ClFN2OS.
What is the molecular weight of (2E)-3-(4-chlorophenyl)-N-[5-(4-fluorobenzyl)-1,3-thiazol-2-yl]-2-propenamide?
The molecular weight of (2E)-3-(4-chlorophenyl)-N-[5-(4-fluorobenzyl)-1,3-thiazol-2-yl]-2-propenamide is 372.05 g/mol.
Where can I buy (2E)-3-(4-chlorophenyl)-N-[5-(4-fluorobenzyl)-1,3-thiazol-2-yl]-2-propenamide?
You can request a quote for (2E)-3-(4-chlorophenyl)-N-[5-(4-fluorobenzyl)-1,3-thiazol-2-yl]-2-propenamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2E)-3-(4-chlorophenyl)-N-[5-(4-fluorobenzyl)-1,3-thiazol-2-yl]-2-propenamide?
Yes, KEHONG BIO provides custom synthesis services for (2E)-3-(4-chlorophenyl)-N-[5-(4-fluorobenzyl)-1,3-thiazol-2-yl]-2-propenamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.