ER-127528 free base
TL;DR: ER-127528 free base (CAS 290308-83-7) is a chemical compound with molecular formula C24H27F2NO3 and molecular weight 415.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-fluoro-2-[[1-[(3-fluorophenyl)methyl]piperidin-4-yl]methyl]-5,6-dimethoxy-3H-inden-1-one
Also Known As: ER-127528 free base, 1H-Inden-1-one, 2-fluoro-2-((1-((3-fluorophenyl)methyl)-4-piperidinyl)methyl)-2,3-dihydro-5,6-dimethoxy-, 2-fluoro-2-[[1-[(3-fluorophenyl)methyl]-4-piperidyl]methyl]-5,6-dimethoxy-3H-inden-1-one
| Molecular Formula | C24H27F2NO3 |
|---|---|
| Molecular Weight | 415.20 g/mol |
| LogP | 4.5923 |
| Topological Polar Surface Area | 38.77 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 415.1959 |
| Heavy Atoms | 30 |
| Complexity | 940.04346 |
Chemical Identifiers
| CAS Number | 290308-83-7 |
|---|---|
| SMILES | COC1=C(C=C2C(=C1)CC(C2=O)(CC3CCN(CC3)CC4=CC(=CC=C4)F)F)OC |
Product Overview
ER-127528 free base (CAS 290308-83-7), with molecular formula C24H27F2NO3 and molecular weight 415.20 g/mol. IUPAC: 2-fluoro-2-[[1-[(3-fluorophenyl)methyl]piperidin-4-yl]methyl]-5,6-dimethoxy-3H-inden-1-one.
Chemical Property Profile of ER-127528 free base
Property Insights of ER-127528 free base
The XLogP value of 4.5923 indicates that ER-127528 free base is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 38.77 Ų, ER-127528 free base exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, ER-127528 free base has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of ER-127528 free base?
The CAS number of ER-127528 free base is 290308-83-7.
What is the molecular formula of ER-127528 free base?
The molecular formula of ER-127528 free base is C24H27F2NO3.
What is the molecular weight of ER-127528 free base?
The molecular weight of ER-127528 free base is 415.20 g/mol.
Where can I buy ER-127528 free base?
You can request a quote for ER-127528 free base directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for ER-127528 free base?
Yes, KEHONG BIO provides custom synthesis services for ER-127528 free base and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.