![N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide structure](/static/products/289/289677-03-8.png)
N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide
TL;DR: N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide (CAS 289677-03-8) is a chemical compound with molecular formula C16H10F3N3O and molecular weight 317.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide
Also Known As: Peakdale1_000093, N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide, 1,8-Naphthyridine-2-carboxamide, N-[3-(trifluoromethyl)phenyl]-, 1,8-Naphthyridine-2-carboxamide, N-[3-(trifluoromethyl)phenyl]- (9CI)
| Molecular Formula | C16H10F3N3O |
|---|---|
| Molecular Weight | 317.08 g/mol |
| LogP | 3.9009 |
| Topological Polar Surface Area | 54.88 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 317.0776 |
| Heavy Atoms | 23 |
| Complexity | 877.5735 |
Chemical Identifiers
| CAS Number | 289677-03-8 |
|---|---|
| SMILES | C1=CC(=CC(=C1)NC(=O)C2=NC3=C(C=CC=N3)C=C2)C(F)(F)F |
Product Overview
N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide (CAS 289677-03-8), with molecular formula C16H10F3N3O and molecular weight 317.08 g/mol. IUPAC: N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide.
Chemical Property Profile of N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide
Property Insights of N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide
The XLogP value of 3.9009 indicates that N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.88 Ų, N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide?
The CAS number of N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide is 289677-03-8.
What is the molecular formula of N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide?
The molecular formula of N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide is C16H10F3N3O.
What is the molecular weight of N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide?
The molecular weight of N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide is 317.08 g/mol.
Where can I buy N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide?
You can request a quote for N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.