trans-Amorolfine
TL;DR: trans-Amorolfine (CAS 288583-03-9) is a chemical compound with molecular formula C21H35NO and molecular weight 317.27 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S,6S)-2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine
Also Known As: trans-Amorolfine, Amorolfine, AMOROLFINE EP IMPURITY E, (2S,6S)-2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine, Morpholine, 4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-, (2R,6R)-rel-; (2RS,6RS)-2,6-Dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine; (2RS,6RS)-4-[3-[4-(1,1-Dimethylpropyl)phenyl]-2-methyl-propyl]-2,6-dimethyl-morpholine; trans-Amorolfine
| Molecular Formula | C21H35NO |
|---|---|
| Molecular Weight | 317.27 g/mol |
| LogP | 4.662 |
| Topological Polar Surface Area | 12.47 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 6 |
| Exact Mass | 317.27185 |
| Heavy Atoms | 23 |
| Complexity | 469.11987 |
Chemical Identifiers
| CAS Number | 288583-03-9 |
|---|---|
| SMILES | CCC(C)(C)C1=CC=C(C=C1)CC(C)CN2C[C@@H](O[C@H](C2)C)C |
Product Overview
trans-Amorolfine (CAS 288583-03-9), with molecular formula C21H35NO and molecular weight 317.27 g/mol. IUPAC: (2S,6S)-2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine.
Chemical Property Profile of trans-Amorolfine
Property Insights of trans-Amorolfine
The XLogP value of 4.662 indicates that trans-Amorolfine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.47 Ų, trans-Amorolfine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, trans-Amorolfine has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of trans-Amorolfine?
The CAS number of trans-Amorolfine is 288583-03-9.
What is the molecular formula of trans-Amorolfine?
The molecular formula of trans-Amorolfine is C21H35NO.
What is the molecular weight of trans-Amorolfine?
The molecular weight of trans-Amorolfine is 317.27 g/mol.
Where can I buy trans-Amorolfine?
You can request a quote for trans-Amorolfine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for trans-Amorolfine?
Yes, KEHONG BIO provides custom synthesis services for trans-Amorolfine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.