N3-(2,4-Difluorophenyl)-2-chloro-4-(trifluoromethyl)nicotinamide
TL;DR: N3-(2,4-Difluorophenyl)-2-chloro-4-(trifluoromethyl)nicotinamide (CAS 288246-33-3) is a chemical compound with molecular formula C13H6ClF5N2O and molecular weight 336.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-N-(2,4-difluorophenyl)-4-(trifluoromethyl)pyridine-3-carboxamide
Also Known As: N3-(2,4-Difluorophenyl)-2-chloro-4-(trifluoromethyl)nicotinamide, 2-chloro-N-(2,4-difluorophenyl)-4-(trifluoromethyl)pyridine-3-carboxamide, 2-Chloro-N-(2,4-difluorophenyl)-4-(trifluoromethyl)nicotinamide
| Molecular Formula | C13H6ClF5N2O |
|---|---|
| Molecular Weight | 336.01 g/mol |
| LogP | 4.2843 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 336.00888 |
| Heavy Atoms | 22 |
| Complexity | 732.8558 |
Chemical Identifiers
| CAS Number | 288246-33-3 |
|---|---|
| SMILES | C1=CC(=C(C=C1F)F)NC(=O)C2=C(C=CN=C2Cl)C(F)(F)F |
Product Overview
N3-(2,4-Difluorophenyl)-2-chloro-4-(trifluoromethyl)nicotinamide (CAS 288246-33-3), with molecular formula C13H6ClF5N2O and molecular weight 336.01 g/mol. IUPAC: 2-chloro-N-(2,4-difluorophenyl)-4-(trifluoromethyl)pyridine-3-carboxamide.
Chemical Property Profile of N3-(2,4-Difluorophenyl)-2-chloro-4-(trifluoromethyl)nicotinamide
Property Insights of N3-(2,4-Difluorophenyl)-2-chloro-4-(trifluoromethyl)nicotinamide
The XLogP value of 4.2843 indicates that N3-(2,4-Difluorophenyl)-2-chloro-4-(trifluoromethyl)nicotinamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, N3-(2,4-Difluorophenyl)-2-chloro-4-(trifluoromethyl)nicotinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N3-(2,4-Difluorophenyl)-2-chloro-4-(trifluoromethyl)nicotinamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N3-(2,4-Difluorophenyl)-2-chloro-4-(trifluoromethyl)nicotinamide?
The CAS number of N3-(2,4-Difluorophenyl)-2-chloro-4-(trifluoromethyl)nicotinamide is 288246-33-3.
What is the molecular formula of N3-(2,4-Difluorophenyl)-2-chloro-4-(trifluoromethyl)nicotinamide?
The molecular formula of N3-(2,4-Difluorophenyl)-2-chloro-4-(trifluoromethyl)nicotinamide is C13H6ClF5N2O.
What is the molecular weight of N3-(2,4-Difluorophenyl)-2-chloro-4-(trifluoromethyl)nicotinamide?
The molecular weight of N3-(2,4-Difluorophenyl)-2-chloro-4-(trifluoromethyl)nicotinamide is 336.01 g/mol.
Where can I buy N3-(2,4-Difluorophenyl)-2-chloro-4-(trifluoromethyl)nicotinamide?
You can request a quote for N3-(2,4-Difluorophenyl)-2-chloro-4-(trifluoromethyl)nicotinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N3-(2,4-Difluorophenyl)-2-chloro-4-(trifluoromethyl)nicotinamide?
Yes, KEHONG BIO provides custom synthesis services for N3-(2,4-Difluorophenyl)-2-chloro-4-(trifluoromethyl)nicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.