Zepastine structure

Zepastine

TL;DR: Zepastine (CAS 28810-23-3) is a chemical compound with molecular formula C22H26N2O3S and molecular weight 398.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

6-methyl-11-[(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)oxy]-11H-benzo[c][1,2]benzothiazepine 5,5-dioxide

Also Known As: Zepastine, 6-methyl-11-[(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)oxy]-11H-benzo[c][1,2]benzothiazepine 5,5-dioxide

CAS: 28810-23-3
Molecular Formula C22H26N2O3S
Molecular Weight 398.17 g/mol
LogP 3.5563
Topological Polar Surface Area 49.85 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 2
Exact Mass 398.1664
Heavy Atoms 28
Complexity 992.3464

Chemical Identifiers

CAS Number 28810-23-3
SMILES CN1C2CCC1CC(C2)OC3C4=CC=CC=C4N(S(=O)(=O)C5=CC=CC=C35)C

Product Overview

Zepastine (CAS 28810-23-3), with molecular formula C22H26N2O3S and molecular weight 398.17 g/mol. IUPAC: 6-methyl-11-[(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)oxy]-11H-benzo[c][1,2]benzothiazepine 5,5-dioxide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Zepastine

XLogP
3.5563
TPSA (Topological Polar Surface Area)
49.85
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
2
Heavy Atoms
28
Complexity
992.3464
Exact Mass
398.1664
Monoisotopic Mass
398.1664
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Zepastine

The XLogP value of 3.5563 indicates that Zepastine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.85 Ų, Zepastine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Zepastine has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Zepastine?

The CAS number of Zepastine is 28810-23-3.

What is the molecular formula of Zepastine?

The molecular formula of Zepastine is C22H26N2O3S.

What is the molecular weight of Zepastine?

The molecular weight of Zepastine is 398.17 g/mol.

Where can I buy Zepastine?

You can request a quote for Zepastine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Zepastine?

Yes, KEHONG BIO provides custom synthesis services for Zepastine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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