Thiofedrine
TL;DR: Thiofedrine (CAS 28745-68-8) is a chemical compound with molecular formula C16H19NO2S and molecular weight 289.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[(1-hydroxy-1-phenylpropan-2-yl)amino]-1-thiophen-2-ylpropan-1-one
Also Known As: Thiofedrine, 1-Propanone,3-( -1- -, 2-(3-(2-Phenyl-2-hydroxyl-1-methylethylamino)propiono)thiophene, 3-[(1-hydroxy-1-phenylpropan-2-yl)amino]-1-thiophen-2-ylpropan-1-one, 1-Propanone, 3-((2-hydroxy-1-methyl-2-phenylethyl)amino)-1-(2-thienyl)-
| Molecular Formula | C16H19NO2S |
|---|---|
| Molecular Weight | 289.11 g/mol |
| LogP | 3.0326 |
| Topological Polar Surface Area | 49.33 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 7 |
| Exact Mass | 289.11365 |
| Heavy Atoms | 20 |
| Complexity | 524.6746 |
Chemical Identifiers
| CAS Number | 28745-68-8 |
|---|---|
| SMILES | CC(C(C1=CC=CC=C1)O)NCCC(=O)C2=CC=CS2 |
Product Overview
Thiofedrine (CAS 28745-68-8), with molecular formula C16H19NO2S and molecular weight 289.11 g/mol. IUPAC: 3-[(1-hydroxy-1-phenylpropan-2-yl)amino]-1-thiophen-2-ylpropan-1-one.
Chemical Property Profile of Thiofedrine
Property Insights of Thiofedrine
The XLogP value of 3.0326 indicates that Thiofedrine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.33 Ų, Thiofedrine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Thiofedrine has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Thiofedrine?
The CAS number of Thiofedrine is 28745-68-8.
What is the molecular formula of Thiofedrine?
The molecular formula of Thiofedrine is C16H19NO2S.
What is the molecular weight of Thiofedrine?
The molecular weight of Thiofedrine is 289.11 g/mol.
Where can I buy Thiofedrine?
You can request a quote for Thiofedrine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Thiofedrine?
Yes, KEHONG BIO provides custom synthesis services for Thiofedrine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.