2-(Dimethylamino)-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile
TL;DR: 2-(Dimethylamino)-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile (CAS 286430-62-4) is a chemical compound with molecular formula C13H10F3N3S and molecular weight 297.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(dimethylamino)-6-thiophen-2-yl-4-(trifluoromethyl)pyridine-3-carbonitrile
Also Known As: 2-(dimethylamino)-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile, 2-(dimethylamino)-6-thiophen-2-yl-4-(trifluoromethyl)pyridine-3-carbonitrile, 3-[(4-METHOXYPHENYL)SULFONYL]PROPANOICACID, 3-Pyridinecarbonitrile, 2-(dimethylamino)-6-(2-thienyl)-4-(trifluoromethyl)-, 2-dimethylamino-6-thiophen-2-yl-4-(trifluoromethyl)pyridine-3-carbonitrile
| Molecular Formula | C13H10F3N3S |
|---|---|
| Molecular Weight | 297.05 g/mol |
| LogP | 3.76658 |
| Topological Polar Surface Area | 39.92 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 297.05475 |
| Heavy Atoms | 20 |
| Complexity | 654.7314 |
Chemical Identifiers
| CAS Number | 286430-62-4 |
|---|---|
| SMILES | CN(C)C1=C(C(=CC(=N1)C2=CC=CS2)C(F)(F)F)C#N |
Product Overview
2-(Dimethylamino)-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile (CAS 286430-62-4), with molecular formula C13H10F3N3S and molecular weight 297.05 g/mol. IUPAC: 2-(dimethylamino)-6-thiophen-2-yl-4-(trifluoromethyl)pyridine-3-carbonitrile.
Chemical Property Profile of 2-(Dimethylamino)-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile
Property Insights of 2-(Dimethylamino)-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile
The XLogP value of 3.76658 indicates that 2-(Dimethylamino)-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 39.92 Ų, 2-(Dimethylamino)-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(Dimethylamino)-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(Dimethylamino)-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile?
The CAS number of 2-(Dimethylamino)-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile is 286430-62-4.
What is the molecular formula of 2-(Dimethylamino)-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile?
The molecular formula of 2-(Dimethylamino)-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile is C13H10F3N3S.
What is the molecular weight of 2-(Dimethylamino)-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile?
The molecular weight of 2-(Dimethylamino)-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile is 297.05 g/mol.
Where can I buy 2-(Dimethylamino)-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile?
You can request a quote for 2-(Dimethylamino)-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(Dimethylamino)-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile?
Yes, KEHONG BIO provides custom synthesis services for 2-(Dimethylamino)-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.