2-Chloro-6-(2-thienyl)-4-(trifluoromethyl)nicotinamide
TL;DR: 2-Chloro-6-(2-thienyl)-4-(trifluoromethyl)nicotinamide (CAS 286430-59-9) is a chemical compound with molecular formula C11H6ClF3N2OS and molecular weight 305.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-6-thiophen-2-yl-4-(trifluoromethyl)pyridine-3-carboxamide
Also Known As: 2-Chloro-6-(2-thienyl)-4-(trifluoromethyl)nicotinamide, 2-chloro-6-(thiophen-2-yl)-4-(trifluoromethyl)pyridine-3-carboxamide, 2-chloro-6-thiophen-2-yl-4-(trifluoromethyl)pyridine-3-carboxamide, 3-Pyridinecarboxamide, 2-chloro-6-(2-thienyl)-4-(trifluoromethyl)-, 2-Chloro-6-(2-thienyl)-4-(trifluoromethyl)-3-pyridinecarboxamide
| Molecular Formula | C11H6ClF3N2OS |
|---|---|
| Molecular Weight | 305.98 g/mol |
| LogP | 3.5812 |
| Topological Polar Surface Area | 55.98 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 305.98416 |
| Heavy Atoms | 19 |
| Complexity | 625.6108 |
Chemical Identifiers
| CAS Number | 286430-59-9 |
|---|---|
| SMILES | C1=CSC(=C1)C2=NC(=C(C(=C2)C(F)(F)F)C(=O)N)Cl |
Product Overview
2-Chloro-6-(2-thienyl)-4-(trifluoromethyl)nicotinamide (CAS 286430-59-9), with molecular formula C11H6ClF3N2OS and molecular weight 305.98 g/mol. IUPAC: 2-chloro-6-thiophen-2-yl-4-(trifluoromethyl)pyridine-3-carboxamide.
Chemical Property Profile of 2-Chloro-6-(2-thienyl)-4-(trifluoromethyl)nicotinamide
Property Insights of 2-Chloro-6-(2-thienyl)-4-(trifluoromethyl)nicotinamide
The XLogP value of 3.5812 indicates that 2-Chloro-6-(2-thienyl)-4-(trifluoromethyl)nicotinamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.98 Ų, 2-Chloro-6-(2-thienyl)-4-(trifluoromethyl)nicotinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Chloro-6-(2-thienyl)-4-(trifluoromethyl)nicotinamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Chloro-6-(2-thienyl)-4-(trifluoromethyl)nicotinamide?
The CAS number of 2-Chloro-6-(2-thienyl)-4-(trifluoromethyl)nicotinamide is 286430-59-9.
What is the molecular formula of 2-Chloro-6-(2-thienyl)-4-(trifluoromethyl)nicotinamide?
The molecular formula of 2-Chloro-6-(2-thienyl)-4-(trifluoromethyl)nicotinamide is C11H6ClF3N2OS.
What is the molecular weight of 2-Chloro-6-(2-thienyl)-4-(trifluoromethyl)nicotinamide?
The molecular weight of 2-Chloro-6-(2-thienyl)-4-(trifluoromethyl)nicotinamide is 305.98 g/mol.
Where can I buy 2-Chloro-6-(2-thienyl)-4-(trifluoromethyl)nicotinamide?
You can request a quote for 2-Chloro-6-(2-thienyl)-4-(trifluoromethyl)nicotinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Chloro-6-(2-thienyl)-4-(trifluoromethyl)nicotinamide?
Yes, KEHONG BIO provides custom synthesis services for 2-Chloro-6-(2-thienyl)-4-(trifluoromethyl)nicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.