Preparation 141
TL;DR: Preparation 141 (CAS 28536-30-3) is a chemical compound with molecular formula C20H28N5O2P and molecular weight 401.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[bis(aziridin-1-yl)phosphoryl]-2,6-dimethyl-5-[(4-propan-2-yloxyphenyl)methyl]pyrimidin-4-amine
Also Known As: Preparation 141, Phosphinic amide, P,P-bis(1-aziridinyl)-N-(5-(p-isopropoxybenzyl)-2,6-dimethyl-4-pyrimidinyl)-, 2,4-Dimethyl-5-(4-isopropoxybenzyl)pyrimid-6-ylaminophosphoric acid diethylenimide, N-[bis(aziridin-1-yl)phosphoryl]-2,6-dimethyl-5-[(4-propan-2-yloxyphenyl)methyl]pyrimidin-4-amine, P,P-Bis(aziridin-1-yl)-N-[2,6-dimethyl-5-({4-[(propan-2-yl)oxy]phenyl}methyl)pyrimidin-4-yl]phosphinic amide
| Molecular Formula | C20H28N5O2P |
|---|---|
| Molecular Weight | 401.20 g/mol |
| LogP | 3.4 |
| Topological Polar Surface Area | 70.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 8 |
| Exact Mass | 401.19806 |
| Heavy Atoms | 28 |
| Complexity | 559.0 |
Chemical Identifiers
| CAS Number | 28536-30-3 |
|---|---|
| SMILES | CC1=C(C(=NC(=N1)C)NP(=O)(N2CC2)N3CC3)CC4=CC=C(C=C4)OC(C)C |
| InChIKey | FTNFEHXDETWERN-UHFFFAOYSA-N |
Product Overview
Preparation 141 (CAS 28536-30-3), with molecular formula C20H28N5O2P and molecular weight 401.20 g/mol. IUPAC: N-[bis(aziridin-1-yl)phosphoryl]-2,6-dimethyl-5-[(4-propan-2-yloxyphenyl)methyl]pyrimidin-4-amine.
Chemical Property Profile of Preparation 141
Property Insights of Preparation 141
The XLogP value of 3.4 indicates that Preparation 141 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 70.1 Ų falls within the moderate polarity range, balancing permeability and solubility for Preparation 141. Following Lipinski's Rule of Five, Preparation 141 has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Preparation 141?
The CAS number of Preparation 141 is 28536-30-3.
What is the molecular formula of Preparation 141?
The molecular formula of Preparation 141 is C20H28N5O2P.
What is the molecular weight of Preparation 141?
The molecular weight of Preparation 141 is 401.20 g/mol.
Where can I buy Preparation 141?
You can request a quote for Preparation 141 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Preparation 141?
Yes, KEHONG BIO provides custom synthesis services for Preparation 141 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.