7-Chloro-3-(4-trifluoromethyl-benzyl)-3H-quinazolin-4-one
TL;DR: 7-Chloro-3-(4-trifluoromethyl-benzyl)-3H-quinazolin-4-one (CAS 284683-22-3) is a chemical compound with molecular formula C16H10ClF3N2O and molecular weight 338.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-chloro-3-[[4-(trifluoromethyl)phenyl]methyl]quinazolin-4-one
Also Known As: 7-chloro-3-[[4-(trifluoromethyl)phenyl]methyl]quinazolin-4-one, 7-CHLORO-3-(4-TRIFLUOROMETHYL-BENZYL)-3H-QUINAZOLIN-4-ONE
| Molecular Formula | C16H10ClF3N2O |
|---|---|
| Molecular Weight | 338.04 g/mol |
| LogP | 4.117 |
| Topological Polar Surface Area | 34.89 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 338.04337 |
| Heavy Atoms | 23 |
| Complexity | 917.24207 |
Chemical Identifiers
| CAS Number | 284683-22-3 |
|---|---|
| SMILES | C1=CC(=CC=C1CN2C=NC3=C(C2=O)C=CC(=C3)Cl)C(F)(F)F |
Product Overview
7-Chloro-3-(4-trifluoromethyl-benzyl)-3H-quinazolin-4-one (CAS 284683-22-3), with molecular formula C16H10ClF3N2O and molecular weight 338.04 g/mol. IUPAC: 7-chloro-3-[[4-(trifluoromethyl)phenyl]methyl]quinazolin-4-one.
Chemical Property Profile of 7-Chloro-3-(4-trifluoromethyl-benzyl)-3H-quinazolin-4-one
Property Insights of 7-Chloro-3-(4-trifluoromethyl-benzyl)-3H-quinazolin-4-one
The XLogP value of 4.117 indicates that 7-Chloro-3-(4-trifluoromethyl-benzyl)-3H-quinazolin-4-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 34.89 Ų, 7-Chloro-3-(4-trifluoromethyl-benzyl)-3H-quinazolin-4-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 7-Chloro-3-(4-trifluoromethyl-benzyl)-3H-quinazolin-4-one has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-Chloro-3-(4-trifluoromethyl-benzyl)-3H-quinazolin-4-one?
The CAS number of 7-Chloro-3-(4-trifluoromethyl-benzyl)-3H-quinazolin-4-one is 284683-22-3.
What is the molecular formula of 7-Chloro-3-(4-trifluoromethyl-benzyl)-3H-quinazolin-4-one?
The molecular formula of 7-Chloro-3-(4-trifluoromethyl-benzyl)-3H-quinazolin-4-one is C16H10ClF3N2O.
What is the molecular weight of 7-Chloro-3-(4-trifluoromethyl-benzyl)-3H-quinazolin-4-one?
The molecular weight of 7-Chloro-3-(4-trifluoromethyl-benzyl)-3H-quinazolin-4-one is 338.04 g/mol.
Where can I buy 7-Chloro-3-(4-trifluoromethyl-benzyl)-3H-quinazolin-4-one?
You can request a quote for 7-Chloro-3-(4-trifluoromethyl-benzyl)-3H-quinazolin-4-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-Chloro-3-(4-trifluoromethyl-benzyl)-3H-quinazolin-4-one?
Yes, KEHONG BIO provides custom synthesis services for 7-Chloro-3-(4-trifluoromethyl-benzyl)-3H-quinazolin-4-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.