4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine
TL;DR: 4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine (CAS 284665-40-3) is a chemical compound with molecular formula C11H6F6N2S and molecular weight 312.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[3,5-bis(trifluoromethyl)phenyl]-1,3-thiazol-2-amine
Also Known As: 4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine, 2-amino-4-(3,5-bis(trifluoromethyl)phenyl)thiazole, 4-[3,5-bis(trifluoromethyl)phenyl]-1,3-thiazol-2-amine, 4-(3,5-bis-trifluoromethylphenyl)thiazol-2-ylamine, BUTTPARK 41\03-38
| Molecular Formula | C11H6F6N2S |
|---|---|
| Molecular Weight | 312.02 g/mol |
| LogP | 4.4299 |
| Topological Polar Surface Area | 38.91 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 312.0156 |
| Heavy Atoms | 20 |
| Complexity | 596.3241 |
Chemical Identifiers
| CAS Number | 284665-40-3 |
|---|---|
| SMILES | C1=C(C=C(C=C1C(F)(F)F)C(F)(F)F)C2=CSC(=N2)N |
Product Overview
4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine (CAS 284665-40-3), with molecular formula C11H6F6N2S and molecular weight 312.02 g/mol. IUPAC: 4-[3,5-bis(trifluoromethyl)phenyl]-1,3-thiazol-2-amine.
Chemical Property Profile of 4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine
Property Insights of 4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine
The XLogP value of 4.4299 indicates that 4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 38.91 Ų, 4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine?
The CAS number of 4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine is 284665-40-3.
What is the molecular formula of 4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine?
The molecular formula of 4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine is C11H6F6N2S.
What is the molecular weight of 4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine?
The molecular weight of 4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine is 312.02 g/mol.
Where can I buy 4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine?
You can request a quote for 4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine?
Yes, KEHONG BIO provides custom synthesis services for 4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.