17-Hydroxy-11,20-dioxopregnane-3,21-diyl diacetate structure

17-Hydroxy-11,20-dioxopregnane-3,21-diyl diacetate

TL;DR: 17-Hydroxy-11,20-dioxopregnane-3,21-diyl diacetate (CAS 28439-40-9) is a chemical compound with molecular formula C25H36O7 and molecular weight 448.25 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[2-(3-acetyloxy-17-hydroxy-10,13-dimethyl-11-oxo-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] acetate

Also Known As: KBio3_002164, Tetrahydrocortisone 3,21-diacetate, 17-hydroxy-11,20-dioxopregnane-3,21-diyl diacetate, 3b,5b-Tetrahydro Cortisone 3,21-Diacetate, 3alpha,17,21-Trihydroxy-5beta-pregnane-11,20-dione 3,21-di(acetate)

CAS: 28439-40-9
Molecular Formula C25H36O7
Molecular Weight 448.25 g/mol
LogP 2.8
Topological Polar Surface Area 107.0 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 7
Rotatable Bonds 6
Exact Mass 448.2461
Heavy Atoms 32
Complexity 836.0

Chemical Identifiers

CAS Number 28439-40-9
SMILES CC(=O)OCC(=O)C1(CCC2C1(CC(=O)C3C2CCC4C3(CCC(C4)OC(=O)C)C)C)O
InChIKey PXQRJZNDFRAFTF-UHFFFAOYSA-N

Product Overview

17-Hydroxy-11,20-dioxopregnane-3,21-diyl diacetate (CAS 28439-40-9), with molecular formula C25H36O7 and molecular weight 448.25 g/mol. IUPAC: [2-(3-acetyloxy-17-hydroxy-10,13-dimethyl-11-oxo-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] acetate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 17-Hydroxy-11,20-dioxopregnane-3,21-diyl diacetate

XLogP
2.8
TPSA (Topological Polar Surface Area)
107.0
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
7
Rotatable Bonds
6
Heavy Atoms
32
Complexity
836.0
Exact Mass
448.2461
Monoisotopic Mass
448.2461
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 17-Hydroxy-11,20-dioxopregnane-3,21-diyl diacetate

The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 17-Hydroxy-11,20-dioxopregnane-3,21-diyl diacetate. The TPSA of 107.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 17-Hydroxy-11,20-dioxopregnane-3,21-diyl diacetate. Following Lipinski's Rule of Five, 17-Hydroxy-11,20-dioxopregnane-3,21-diyl diacetate has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 17-Hydroxy-11,20-dioxopregnane-3,21-diyl diacetate?

The CAS number of 17-Hydroxy-11,20-dioxopregnane-3,21-diyl diacetate is 28439-40-9.

What is the molecular formula of 17-Hydroxy-11,20-dioxopregnane-3,21-diyl diacetate?

The molecular formula of 17-Hydroxy-11,20-dioxopregnane-3,21-diyl diacetate is C25H36O7.

What is the molecular weight of 17-Hydroxy-11,20-dioxopregnane-3,21-diyl diacetate?

The molecular weight of 17-Hydroxy-11,20-dioxopregnane-3,21-diyl diacetate is 448.25 g/mol.

Where can I buy 17-Hydroxy-11,20-dioxopregnane-3,21-diyl diacetate?

You can request a quote for 17-Hydroxy-11,20-dioxopregnane-3,21-diyl diacetate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 17-Hydroxy-11,20-dioxopregnane-3,21-diyl diacetate?

Yes, KEHONG BIO provides custom synthesis services for 17-Hydroxy-11,20-dioxopregnane-3,21-diyl diacetate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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