(17R)-17-(Trimethylsiloxy)-19-norpregn-4-en-20-yn-3-one
TL;DR: (17R)-17-(Trimethylsiloxy)-19-norpregn-4-en-20-yn-3-one (CAS 28426-43-9) is a chemical compound with molecular formula C23H34O2Si and molecular weight 370.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
17-ethynyl-13-methyl-17-trimethylsilyloxy-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
Also Known As: 17-O-Trimethylsilyl Norethindrone, (17R)-17-(Trimethylsiloxy)-19-norpregn-4-en-20-yn-3-one, 17-Ethynyl-17-[(trimethylsilyl)oxy]estr-4-en-3-one, (8R,9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-17-trimethylsilyloxy-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one, 17-ethynyl-13-methyl-17-trimethylsilyloxy-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
| Molecular Formula | C23H34O2Si |
|---|---|
| Molecular Weight | 370.23 g/mol |
| LogP | 5.3517 |
| Topological Polar Surface Area | 26.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 370.23282 |
| Heavy Atoms | 26 |
| Complexity | 693.0 |
Chemical Identifiers
| CAS Number | 28426-43-9 |
|---|---|
| SMILES | CC12CCC3C(C1CCC2(C#C)O[Si](C)(C)C)CCC4=CC(=O)CCC34 |
| InChIKey | LZECAWNJNIQRQF-UHFFFAOYSA-N |
Product Overview
(17R)-17-(Trimethylsiloxy)-19-norpregn-4-en-20-yn-3-one (CAS 28426-43-9), with molecular formula C23H34O2Si and molecular weight 370.23 g/mol. IUPAC: 17-ethynyl-13-methyl-17-trimethylsilyloxy-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one.
Chemical Property Profile of (17R)-17-(Trimethylsiloxy)-19-norpregn-4-en-20-yn-3-one
Property Insights of (17R)-17-(Trimethylsiloxy)-19-norpregn-4-en-20-yn-3-one
The XLogP value of 5.3517 indicates that (17R)-17-(Trimethylsiloxy)-19-norpregn-4-en-20-yn-3-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 26.3 Ų, (17R)-17-(Trimethylsiloxy)-19-norpregn-4-en-20-yn-3-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (17R)-17-(Trimethylsiloxy)-19-norpregn-4-en-20-yn-3-one has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (17R)-17-(Trimethylsiloxy)-19-norpregn-4-en-20-yn-3-one?
The CAS number of (17R)-17-(Trimethylsiloxy)-19-norpregn-4-en-20-yn-3-one is 28426-43-9.
What is the molecular formula of (17R)-17-(Trimethylsiloxy)-19-norpregn-4-en-20-yn-3-one?
The molecular formula of (17R)-17-(Trimethylsiloxy)-19-norpregn-4-en-20-yn-3-one is C23H34O2Si.
What is the molecular weight of (17R)-17-(Trimethylsiloxy)-19-norpregn-4-en-20-yn-3-one?
The molecular weight of (17R)-17-(Trimethylsiloxy)-19-norpregn-4-en-20-yn-3-one is 370.23 g/mol.
Where can I buy (17R)-17-(Trimethylsiloxy)-19-norpregn-4-en-20-yn-3-one?
You can request a quote for (17R)-17-(Trimethylsiloxy)-19-norpregn-4-en-20-yn-3-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (17R)-17-(Trimethylsiloxy)-19-norpregn-4-en-20-yn-3-one?
Yes, KEHONG BIO provides custom synthesis services for (17R)-17-(Trimethylsiloxy)-19-norpregn-4-en-20-yn-3-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.