(E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide
TL;DR: (E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide (CAS 28424-60-4) is a chemical compound with molecular formula C14H13NOS and molecular weight 243.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-(4-methylphenyl)-3-thiophen-2-ylprop-2-enamide
Also Known As: (E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide, (2E)-N-(4-methylphenyl)-3-(thiophen-2-yl)prop-2-enamide, N-p-tolyl-(E)-3-(2-thienyl)acrylamide, (E)-N-(4-methylphenyl)-3-thiophen-2-ylprop-2-enamide, AB00760411-01
| Molecular Formula | C14H13NOS |
|---|---|
| Molecular Weight | 243.07 g/mol |
| LogP | 3.70842 |
| Topological Polar Surface Area | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 243.0718 |
| Heavy Atoms | 17 |
| Complexity | 511.66507 |
Chemical Identifiers
| CAS Number | 28424-60-4 |
|---|---|
| SMILES | CC1=CC=C(C=C1)NC(=O)/C=C/C2=CC=CS2 |
Product Overview
(E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide (CAS 28424-60-4), with molecular formula C14H13NOS and molecular weight 243.07 g/mol. IUPAC: (E)-N-(4-methylphenyl)-3-thiophen-2-ylprop-2-enamide.
Chemical Property Profile of (E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide
Property Insights of (E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide
The XLogP value of 3.70842 indicates that (E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.1 Ų, (E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide?
The CAS number of (E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide is 28424-60-4.
What is the molecular formula of (E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide?
The molecular formula of (E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide is C14H13NOS.
What is the molecular weight of (E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide?
The molecular weight of (E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide is 243.07 g/mol.
Where can I buy (E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide?
You can request a quote for (E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.