Thyrotropin-releasing hormone, beta-(pyrazolyl-1)-ala(2)-
TL;DR: Thyrotropin-releasing hormone, beta-(pyrazolyl-1)-ala(2)- (CAS 28398-28-9) is a chemical compound with molecular formula C16H22N6O4 and molecular weight 362.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-1-oxo-3-(1H-pyrazol-5-yl)propan-2-yl]-5-oxopyrrolidine-2-carboxamide
Also Known As: Pyrala, Bpa-TRH, TRH, beta(pyrazolyl-1)-ala(2)-, Thyrotropin-releasing hormone, beta-(pyrazolyl-1)-ala(2)-, beta-(Pyrazolyl-1)-2-ala-thyrotropin-releasing hormone
| Molecular Formula | C16H22N6O4 |
|---|---|
| Molecular Weight | 362.17 g/mol |
| LogP | -1.8081 |
| Topological Polar Surface Area | 150.28 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 362.17026 |
| Heavy Atoms | 26 |
| Complexity | 703.60297 |
Chemical Identifiers
| CAS Number | 28398-28-9 |
|---|---|
| SMILES | C1C[C@H](N(C1)C(=O)[C@H](CC2=CC=NN2)NC(=O)[C@@H]3CCC(=O)N3)C(=O)N |
Product Overview
Thyrotropin-releasing hormone, beta-(pyrazolyl-1)-ala(2)- (CAS 28398-28-9), with molecular formula C16H22N6O4 and molecular weight 362.17 g/mol. IUPAC: (2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-1-oxo-3-(1H-pyrazol-5-yl)propan-2-yl]-5-oxopyrrolidine-2-carboxamide.
Chemical Property Profile of Thyrotropin-releasing hormone, beta-(pyrazolyl-1)-ala(2)-
Property Insights of Thyrotropin-releasing hormone, beta-(pyrazolyl-1)-ala(2)-
The XLogP value of -1.8081 indicates that Thyrotropin-releasing hormone, beta-(pyrazolyl-1)-ala(2)- is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 150.28 Ų indicates high polarity, suggesting Thyrotropin-releasing hormone, beta-(pyrazolyl-1)-ala(2)- may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Thyrotropin-releasing hormone, beta-(pyrazolyl-1)-ala(2)- has 4 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Thyrotropin-releasing hormone, beta-(pyrazolyl-1)-ala(2)-?
The CAS number of Thyrotropin-releasing hormone, beta-(pyrazolyl-1)-ala(2)- is 28398-28-9.
What is the molecular formula of Thyrotropin-releasing hormone, beta-(pyrazolyl-1)-ala(2)-?
The molecular formula of Thyrotropin-releasing hormone, beta-(pyrazolyl-1)-ala(2)- is C16H22N6O4.
What is the molecular weight of Thyrotropin-releasing hormone, beta-(pyrazolyl-1)-ala(2)-?
The molecular weight of Thyrotropin-releasing hormone, beta-(pyrazolyl-1)-ala(2)- is 362.17 g/mol.
Where can I buy Thyrotropin-releasing hormone, beta-(pyrazolyl-1)-ala(2)-?
You can request a quote for Thyrotropin-releasing hormone, beta-(pyrazolyl-1)-ala(2)- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Thyrotropin-releasing hormone, beta-(pyrazolyl-1)-ala(2)-?
Yes, KEHONG BIO provides custom synthesis services for Thyrotropin-releasing hormone, beta-(pyrazolyl-1)-ala(2)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.