Methylcolchaminone
TL;DR: Methylcolchaminone (CAS 2826-80-4) is a chemical compound with molecular formula C22H26N2O5 and molecular weight 398.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(7S)-1,2,3-trimethoxy-10-(methylamino)-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Also Known As: Methylcolchaminone, Methylaminocolchicide, Colchicoinamide, N-Methyl-, N-Methylcolchiceinamide, 10-Demethoxy-10-methylaminocolchicine
| Molecular Formula | C22H26N2O5 |
|---|---|
| Molecular Weight | 398.18 g/mol |
| LogP | 1.5 |
| Topological Polar Surface Area | 85.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 398.18417 |
| Heavy Atoms | 29 |
| Complexity | 741.0 |
Chemical Identifiers
| CAS Number | 2826-80-4 |
|---|---|
| SMILES | CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)NC)OC)OC)OC |
| InChIKey | NLBLGIGBTKMQSA-INIZCTEOSA-N |
Product Overview
Methylcolchaminone (CAS 2826-80-4), with molecular formula C22H26N2O5 and molecular weight 398.18 g/mol. IUPAC: N-[(7S)-1,2,3-trimethoxy-10-(methylamino)-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide.
Chemical Property Profile of Methylcolchaminone
Property Insights of Methylcolchaminone
The XLogP value of 1.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Methylcolchaminone. The TPSA of 85.9 Ų falls within the moderate polarity range, balancing permeability and solubility for Methylcolchaminone. Following Lipinski's Rule of Five, Methylcolchaminone has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Methylcolchaminone?
The CAS number of Methylcolchaminone is 2826-80-4.
What is the molecular formula of Methylcolchaminone?
The molecular formula of Methylcolchaminone is C22H26N2O5.
What is the molecular weight of Methylcolchaminone?
The molecular weight of Methylcolchaminone is 398.18 g/mol.
Where can I buy Methylcolchaminone?
You can request a quote for Methylcolchaminone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Methylcolchaminone?
Yes, KEHONG BIO provides custom synthesis services for Methylcolchaminone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.