Pnu-142774E structure

Pnu-142774E

TL;DR: Pnu-142774E (CAS 282522-93-4) is a chemical compound with molecular formula C11H13N3S and molecular weight 219.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(10R)-10-(methylamino)-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-triene-2-thione

Also Known As: PNU-142774E, (5R)-5-(Methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinoline-2(1H)-thione, 4H-Imidazo[4,5,1-ij]quinoline-2(1H)-thione, 5,6-dihydro-5-(methylamino)-, (5R)-, RefChem:929480

CAS: 282522-93-4
Molecular Formula C11H13N3S
Molecular Weight 219.08 g/mol
LogP 1.84299
Topological Polar Surface Area 32.75 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 2
Rotatable Bonds 1
Exact Mass 219.08302
Heavy Atoms 15
Complexity 566.707

Chemical Identifiers

CAS Number 282522-93-4
SMILES CN[C@@H]1CC2=C3C(=CC=C2)NC(=S)N3C1

Product Overview

Pnu-142774E (CAS 282522-93-4), with molecular formula C11H13N3S and molecular weight 219.08 g/mol. IUPAC: (10R)-10-(methylamino)-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-triene-2-thione.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Pnu-142774E

XLogP
1.84299
TPSA (Topological Polar Surface Area)
32.75
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
2
Rotatable Bonds
1
Heavy Atoms
15
Complexity
566.707
Exact Mass
219.08302
Monoisotopic Mass
219.08302
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Pnu-142774E

The XLogP value of 1.84299 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Pnu-142774E. With a topological polar surface area (TPSA) of 32.75 Ų, Pnu-142774E exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Pnu-142774E has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Pnu-142774E?

The CAS number of Pnu-142774E is 282522-93-4.

What is the molecular formula of Pnu-142774E?

The molecular formula of Pnu-142774E is C11H13N3S.

What is the molecular weight of Pnu-142774E?

The molecular weight of Pnu-142774E is 219.08 g/mol.

Where can I buy Pnu-142774E?

You can request a quote for Pnu-142774E directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Pnu-142774E?

Yes, KEHONG BIO provides custom synthesis services for Pnu-142774E and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

🤖 科弘生物 AI 助手 ×
您好!我是 科弘生物 AI 助手。可以问我产品搜索、询价、样品或技术问题。如何帮助您?