4',5'-Didehydro-5'-deoxythymidine structure

4',5'-Didehydro-5'-deoxythymidine

TL;DR: 4',5'-Didehydro-5'-deoxythymidine (CAS 28034-72-2) is a chemical compound with molecular formula C10H12N2O4 and molecular weight 224.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-(4-hydroxy-5-methylideneoxolan-2-yl)-5-methylpyrimidine-2,4-dione

Also Known As: 4',5'-Didehydro-5'-deoxythymidine, A4131/0176177, 1-(4-hydroxy-5-methylideneoxolan-2-yl)-5-methylpyrimidine-2,4-dione, 1-(4-hydroxy-5-methylenetetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione, 1-(4-hydroxy-5-methylidenetetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

CAS: 28034-72-2
Molecular Formula C10H12N2O4
Molecular Weight 224.08 g/mol
LogP -0.36148
Topological Polar Surface Area 84.32 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 4
Rotatable Bonds 1
Exact Mass 224.07971
Heavy Atoms 16
Complexity 542.4854

Chemical Identifiers

CAS Number 28034-72-2
SMILES CC1=CN(C(=O)NC1=O)C2CC(C(=C)O2)O

Product Overview

4',5'-Didehydro-5'-deoxythymidine (CAS 28034-72-2), with molecular formula C10H12N2O4 and molecular weight 224.08 g/mol. IUPAC: 1-(4-hydroxy-5-methylideneoxolan-2-yl)-5-methylpyrimidine-2,4-dione.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 4',5'-Didehydro-5'-deoxythymidine

XLogP
-0.36148
TPSA (Topological Polar Surface Area)
84.32
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
4
Rotatable Bonds
1
Heavy Atoms
16
Complexity
542.4854
Exact Mass
224.07971
Monoisotopic Mass
224.07971
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 4',5'-Didehydro-5'-deoxythymidine

The XLogP value of -0.36148 indicates that 4',5'-Didehydro-5'-deoxythymidine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 84.32 Ų falls within the moderate polarity range, balancing permeability and solubility for 4',5'-Didehydro-5'-deoxythymidine. Following Lipinski's Rule of Five, 4',5'-Didehydro-5'-deoxythymidine has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 4',5'-Didehydro-5'-deoxythymidine?

The CAS number of 4',5'-Didehydro-5'-deoxythymidine is 28034-72-2.

What is the molecular formula of 4',5'-Didehydro-5'-deoxythymidine?

The molecular formula of 4',5'-Didehydro-5'-deoxythymidine is C10H12N2O4.

What is the molecular weight of 4',5'-Didehydro-5'-deoxythymidine?

The molecular weight of 4',5'-Didehydro-5'-deoxythymidine is 224.08 g/mol.

Where can I buy 4',5'-Didehydro-5'-deoxythymidine?

You can request a quote for 4',5'-Didehydro-5'-deoxythymidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 4',5'-Didehydro-5'-deoxythymidine?

Yes, KEHONG BIO provides custom synthesis services for 4',5'-Didehydro-5'-deoxythymidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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