2',3'-O-Isopropylidene-5-fluorouridine
TL;DR: 2',3'-O-Isopropylidene-5-fluorouridine (CAS 2797-17-3) is a chemical compound with molecular formula C12H15FN2O6 and molecular weight 302.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-fluoro-1-[(4R,6R)-6-(hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]pyrimidine-2,4-dione
Also Known As: 2',3'-O-Isopropylidene-5-fluorouridine, 5-Fluoro-2',3'-O-(1-methylethylidene)uridine, Uridine, 5-fluoro-2',3'-O-(1-methylethylidene)-, 5-fluoro-1-[(4R,6R)-6-(hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]pyrimidine-2,4-dione, 5-fluoro-1-[ -4- -7,7-dimethyl-3,6,8-trioxabicyclo[3.3.0]oct-2-yl]pyrimidine-2,4-dione
| Molecular Formula | C12H15FN2O6 |
|---|---|
| Molecular Weight | 302.09 g/mol |
| LogP | -1.0 |
| Topological Polar Surface Area | 97.3 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 2 |
| Exact Mass | 302.0914 |
| Heavy Atoms | 21 |
| Complexity | 522.0 |
Chemical Identifiers
| CAS Number | 2797-17-3 |
|---|---|
| SMILES | CC1(OC2[C@H](O[C@H](C2O1)N3C=C(C(=O)NC3=O)F)CO)C |
| InChIKey | LHTMLCXJMYPWGR-NPDIDSPYSA-N |
Product Overview
2',3'-O-Isopropylidene-5-fluorouridine (CAS 2797-17-3), with molecular formula C12H15FN2O6 and molecular weight 302.09 g/mol. IUPAC: 5-fluoro-1-[(4R,6R)-6-(hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]pyrimidine-2,4-dione.
Chemical Property Profile of 2',3'-O-Isopropylidene-5-fluorouridine
Property Insights of 2',3'-O-Isopropylidene-5-fluorouridine
The XLogP value of -1.0 indicates that 2',3'-O-Isopropylidene-5-fluorouridine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 97.3 Ų falls within the moderate polarity range, balancing permeability and solubility for 2',3'-O-Isopropylidene-5-fluorouridine. Following Lipinski's Rule of Five, 2',3'-O-Isopropylidene-5-fluorouridine has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2',3'-O-Isopropylidene-5-fluorouridine?
The CAS number of 2',3'-O-Isopropylidene-5-fluorouridine is 2797-17-3.
What is the molecular formula of 2',3'-O-Isopropylidene-5-fluorouridine?
The molecular formula of 2',3'-O-Isopropylidene-5-fluorouridine is C12H15FN2O6.
What is the molecular weight of 2',3'-O-Isopropylidene-5-fluorouridine?
The molecular weight of 2',3'-O-Isopropylidene-5-fluorouridine is 302.09 g/mol.
Where can I buy 2',3'-O-Isopropylidene-5-fluorouridine?
You can request a quote for 2',3'-O-Isopropylidene-5-fluorouridine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2',3'-O-Isopropylidene-5-fluorouridine?
Yes, KEHONG BIO provides custom synthesis services for 2',3'-O-Isopropylidene-5-fluorouridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.