21-Acryloxyprogesterone structure

21-Acryloxyprogesterone

TL;DR: 21-Acryloxyprogesterone (CAS 27953-65-7) is a chemical compound with molecular formula C24H32O4 and molecular weight 384.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[2-[(8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] prop-2-enoate

Also Known As: 21-Acryloxyprogesterone, 3,20-Dioxopregn-4-en-21-yl prop-2-enoate, Pregn-4-ene-3,20-dione, 21-((1-oxo-2-propenyl)oxy)-, [2-[(8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] prop-2-enoate, RefChem:89622

CAS: 27953-65-7
Molecular Formula C24H32O4
Molecular Weight 384.23 g/mol
LogP 3.7
Topological Polar Surface Area 60.4 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 5
Exact Mass 384.23007
Heavy Atoms 28
Complexity 750.0

Chemical Identifiers

CAS Number 27953-65-7
SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)COC(=O)C=C)CCC4=CC(=O)CC[C@]34C
InChIKey BIFACLOIZIKJPO-ZEQQQVMLSA-N

Product Overview

21-Acryloxyprogesterone (CAS 27953-65-7), with molecular formula C24H32O4 and molecular weight 384.23 g/mol. IUPAC: [2-[(8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] prop-2-enoate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 21-Acryloxyprogesterone

XLogP
3.7
TPSA (Topological Polar Surface Area)
60.4
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
5
Heavy Atoms
28
Complexity
750.0
Exact Mass
384.23007
Monoisotopic Mass
384.23007
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 21-Acryloxyprogesterone

The XLogP value of 3.7 indicates that 21-Acryloxyprogesterone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 60.4 Ų falls within the moderate polarity range, balancing permeability and solubility for 21-Acryloxyprogesterone. Following Lipinski's Rule of Five, 21-Acryloxyprogesterone has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 21-Acryloxyprogesterone?

The CAS number of 21-Acryloxyprogesterone is 27953-65-7.

What is the molecular formula of 21-Acryloxyprogesterone?

The molecular formula of 21-Acryloxyprogesterone is C24H32O4.

What is the molecular weight of 21-Acryloxyprogesterone?

The molecular weight of 21-Acryloxyprogesterone is 384.23 g/mol.

Where can I buy 21-Acryloxyprogesterone?

You can request a quote for 21-Acryloxyprogesterone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 21-Acryloxyprogesterone?

Yes, KEHONG BIO provides custom synthesis services for 21-Acryloxyprogesterone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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