Niaprazine trihydrochloride
TL;DR: Niaprazine trihydrochloride (CAS 27922-25-4) is a chemical compound with molecular formula C20H28Cl3FN4O and molecular weight 464.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[4-[4-(4-fluorophenyl)piperazin-1-yl]butan-2-yl]pyridine-3-carboxamide;trihydrochloride
Also Known As: Niaprazine trihydrochloride, Niaprazine HCl, 1-(4-Fluorophenyl)-4-(3-(3-pyridoyl)amino)butylpiperazine trihydrochloride, 3-Pyridinecarboxamide, N-(3-(4-(4-fluorophenyl)-1-piperazinyl)-1-methylpropyl)-, 3HCl, N-(3-(4-(p-Fluorophenyl)-1-piperazinyl)-1-methylpropyl)nicotinamide trihydrochloride
| Molecular Formula | C20H28Cl3FN4O |
|---|---|
| Molecular Weight | 464.13 g/mol |
| LogP | 3.8167 |
| Topological Polar Surface Area | 48.5 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 464.1313 |
| Heavy Atoms | 29 |
| Complexity | 434.0 |
Chemical Identifiers
| CAS Number | 27922-25-4 |
|---|---|
| SMILES | CC(CCN1CCN(CC1)C2=CC=C(C=C2)F)NC(=O)C3=CN=CC=C3.Cl.Cl.Cl |
| InChIKey | XWYGMQFKVNQWHV-UHFFFAOYSA-N |
Product Overview
Niaprazine trihydrochloride (CAS 27922-25-4), with molecular formula C20H28Cl3FN4O and molecular weight 464.13 g/mol. IUPAC: N-[4-[4-(4-fluorophenyl)piperazin-1-yl]butan-2-yl]pyridine-3-carboxamide;trihydrochloride.
Chemical Property Profile of Niaprazine trihydrochloride
Property Insights of Niaprazine trihydrochloride
The XLogP value of 3.8167 indicates that Niaprazine trihydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 48.5 Ų, Niaprazine trihydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Niaprazine trihydrochloride has 4 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Niaprazine trihydrochloride?
The CAS number of Niaprazine trihydrochloride is 27922-25-4.
What is the molecular formula of Niaprazine trihydrochloride?
The molecular formula of Niaprazine trihydrochloride is C20H28Cl3FN4O.
What is the molecular weight of Niaprazine trihydrochloride?
The molecular weight of Niaprazine trihydrochloride is 464.13 g/mol.
Where can I buy Niaprazine trihydrochloride?
You can request a quote for Niaprazine trihydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Niaprazine trihydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Niaprazine trihydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.