![1-[4-(Trifluoromethyl)phenyl]piperidin-2-one structure](/static/products/2747/27471-52-9.webp)
1-[4-(Trifluoromethyl)phenyl]piperidin-2-one
TL;DR: 1-[4-(Trifluoromethyl)phenyl]piperidin-2-one (CAS 27471-52-9) is a chemical compound with molecular formula C12H12F3NO and molecular weight 243.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[4-(trifluoromethyl)phenyl]piperidin-2-one
Also Known As: 1-[4-(trifluoromethyl)phenyl]piperidin-2-one, phenyl)piperidin-2-one, Maybridge3_002944, 1-(4-(trifluoromethyl), 2,5-Dihydroxyphenylacetic acid
| Molecular Formula | C12H12F3NO |
|---|---|
| Molecular Weight | 243.09 g/mol |
| LogP | 3.2223 |
| Topological Polar Surface Area | 20.31 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 243.0871 |
| Heavy Atoms | 17 |
| Complexity | 410.75406 |
Chemical Identifiers
| CAS Number | 27471-52-9 |
|---|---|
| SMILES | C1CCN(C(=O)C1)C2=CC=C(C=C2)C(F)(F)F |
Product Overview
1-[4-(Trifluoromethyl)phenyl]piperidin-2-one (CAS 27471-52-9), with molecular formula C12H12F3NO and molecular weight 243.09 g/mol. IUPAC: 1-[4-(trifluoromethyl)phenyl]piperidin-2-one.
Chemical Property Profile of 1-[4-(Trifluoromethyl)phenyl]piperidin-2-one
Property Insights of 1-[4-(Trifluoromethyl)phenyl]piperidin-2-one
The XLogP value of 3.2223 indicates that 1-[4-(Trifluoromethyl)phenyl]piperidin-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 20.31 Ų, 1-[4-(Trifluoromethyl)phenyl]piperidin-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-[4-(Trifluoromethyl)phenyl]piperidin-2-one has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[4-(Trifluoromethyl)phenyl]piperidin-2-one?
The CAS number of 1-[4-(Trifluoromethyl)phenyl]piperidin-2-one is 27471-52-9.
What is the molecular formula of 1-[4-(Trifluoromethyl)phenyl]piperidin-2-one?
The molecular formula of 1-[4-(Trifluoromethyl)phenyl]piperidin-2-one is C12H12F3NO.
What is the molecular weight of 1-[4-(Trifluoromethyl)phenyl]piperidin-2-one?
The molecular weight of 1-[4-(Trifluoromethyl)phenyl]piperidin-2-one is 243.09 g/mol.
Where can I buy 1-[4-(Trifluoromethyl)phenyl]piperidin-2-one?
You can request a quote for 1-[4-(Trifluoromethyl)phenyl]piperidin-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[4-(Trifluoromethyl)phenyl]piperidin-2-one?
Yes, KEHONG BIO provides custom synthesis services for 1-[4-(Trifluoromethyl)phenyl]piperidin-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.