6-(2-Hydroxy-2,2-diphenylethyl)-4-methyl-5-phenyl-2(1H)-pyrimidinone
TL;DR: 6-(2-Hydroxy-2,2-diphenylethyl)-4-methyl-5-phenyl-2(1H)-pyrimidinone (CAS 27433-89-2) is a chemical compound with molecular formula C25H22N2O2 and molecular weight 382.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(2-hydroxy-2,2-diphenylethyl)-6-methyl-5-phenyl-1H-pyrimidin-2-one
Also Known As: NCI60_010845, 2-Hydroxy-4-methyl-5-phenyl-6-[2,2-diphenyl-2-hydroxyethyl]pyrimidine, 6-(2-Hydroxy-2,2-diphenylethyl)-4-methyl-5-phenyl-2(1H)-pyrimidinone, 4-(2-hydroxy-2,2-diphenyl-ethyl)-6-methyl-5-phenyl-pyrimidin-2-ol, 4-(2-Hydroxy-2,2-diphenylethyl)-6-methyl-5-phenyl-2-pyrimidinol
| Molecular Formula | C25H22N2O2 |
|---|---|
| Molecular Weight | 382.17 g/mol |
| LogP | 3.9 |
| Topological Polar Surface Area | 61.7 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 5 |
| Exact Mass | 382.16812 |
| Heavy Atoms | 29 |
| Complexity | 630.0 |
Chemical Identifiers
| CAS Number | 27433-89-2 |
|---|---|
| SMILES | CC1=C(C(=NC(=O)N1)CC(C2=CC=CC=C2)(C3=CC=CC=C3)O)C4=CC=CC=C4 |
| InChIKey | RUMSUGVHLWUDNX-UHFFFAOYSA-N |
Product Overview
6-(2-Hydroxy-2,2-diphenylethyl)-4-methyl-5-phenyl-2(1H)-pyrimidinone (CAS 27433-89-2), with molecular formula C25H22N2O2 and molecular weight 382.17 g/mol. IUPAC: 4-(2-hydroxy-2,2-diphenylethyl)-6-methyl-5-phenyl-1H-pyrimidin-2-one.
Chemical Property Profile of 6-(2-Hydroxy-2,2-diphenylethyl)-4-methyl-5-phenyl-2(1H)-pyrimidinone
Property Insights of 6-(2-Hydroxy-2,2-diphenylethyl)-4-methyl-5-phenyl-2(1H)-pyrimidinone
The XLogP value of 3.9 indicates that 6-(2-Hydroxy-2,2-diphenylethyl)-4-methyl-5-phenyl-2(1H)-pyrimidinone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 61.7 Ų falls within the moderate polarity range, balancing permeability and solubility for 6-(2-Hydroxy-2,2-diphenylethyl)-4-methyl-5-phenyl-2(1H)-pyrimidinone. Following Lipinski's Rule of Five, 6-(2-Hydroxy-2,2-diphenylethyl)-4-methyl-5-phenyl-2(1H)-pyrimidinone has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-(2-Hydroxy-2,2-diphenylethyl)-4-methyl-5-phenyl-2(1H)-pyrimidinone?
The CAS number of 6-(2-Hydroxy-2,2-diphenylethyl)-4-methyl-5-phenyl-2(1H)-pyrimidinone is 27433-89-2.
What is the molecular formula of 6-(2-Hydroxy-2,2-diphenylethyl)-4-methyl-5-phenyl-2(1H)-pyrimidinone?
The molecular formula of 6-(2-Hydroxy-2,2-diphenylethyl)-4-methyl-5-phenyl-2(1H)-pyrimidinone is C25H22N2O2.
What is the molecular weight of 6-(2-Hydroxy-2,2-diphenylethyl)-4-methyl-5-phenyl-2(1H)-pyrimidinone?
The molecular weight of 6-(2-Hydroxy-2,2-diphenylethyl)-4-methyl-5-phenyl-2(1H)-pyrimidinone is 382.17 g/mol.
Where can I buy 6-(2-Hydroxy-2,2-diphenylethyl)-4-methyl-5-phenyl-2(1H)-pyrimidinone?
You can request a quote for 6-(2-Hydroxy-2,2-diphenylethyl)-4-methyl-5-phenyl-2(1H)-pyrimidinone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-(2-Hydroxy-2,2-diphenylethyl)-4-methyl-5-phenyl-2(1H)-pyrimidinone?
Yes, KEHONG BIO provides custom synthesis services for 6-(2-Hydroxy-2,2-diphenylethyl)-4-methyl-5-phenyl-2(1H)-pyrimidinone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.