8-isoprostaglandin E2 structure

8-isoprostaglandin E2

TL;DR: 8-isoprostaglandin E2 (CAS 27415-25-4) is a chemical compound with molecular formula C20H32O5 and molecular weight 352.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

7-[(1S,2R,3R)-3-hydroxy-2-[(3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid

Also Known As: 8-isoprostaglandin E2, 8-Iso-PGE2, Prosta-5,13-dien-1-oicacid, 11,15-dihydroxy-9-oxo-, (5Z,8b,11a,13E,15S)-

CAS: 27415-25-4
Molecular Formula C20H32O5
Molecular Weight 352.22 g/mol
LogP 2.8
Topological Polar Surface Area 94.8 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 5
Rotatable Bonds 12
Exact Mass 352.22498
Heavy Atoms 25
Complexity 469.0

Chemical Identifiers

CAS Number 27415-25-4
SMILES CCCCC[C@@H](C=C[C@H]1[C@@H](CC(=O)[C@H]1CC=CCCCC(=O)O)O)O
InChIKey XEYBRNLFEZDVAW-IMBTUZDBSA-N

Product Overview

8-isoprostaglandin E2 (CAS 27415-25-4), with molecular formula C20H32O5 and molecular weight 352.22 g/mol. IUPAC: 7-[(1S,2R,3R)-3-hydroxy-2-[(3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 8-isoprostaglandin E2

XLogP
2.8
TPSA (Topological Polar Surface Area)
94.8
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
5
Rotatable Bonds
12
Heavy Atoms
25
Complexity
469.0
Exact Mass
352.22498
Monoisotopic Mass
352.22498
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 8-isoprostaglandin E2

The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 8-isoprostaglandin E2. The TPSA of 94.8 Ų falls within the moderate polarity range, balancing permeability and solubility for 8-isoprostaglandin E2. Following Lipinski's Rule of Five, 8-isoprostaglandin E2 has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 8-isoprostaglandin E2?

The CAS number of 8-isoprostaglandin E2 is 27415-25-4.

What is the molecular formula of 8-isoprostaglandin E2?

The molecular formula of 8-isoprostaglandin E2 is C20H32O5.

What is the molecular weight of 8-isoprostaglandin E2?

The molecular weight of 8-isoprostaglandin E2 is 352.22 g/mol.

Where can I buy 8-isoprostaglandin E2?

You can request a quote for 8-isoprostaglandin E2 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 8-isoprostaglandin E2?

Yes, KEHONG BIO provides custom synthesis services for 8-isoprostaglandin E2 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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