![5-{[(E)-(5-chloro-2-hydroxyphenyl)methylidene]amino}pyrimidine-2,4(1H,3H)-dione structure](/static/products/273/273745-71-4.png)
5-{[(E)-(5-chloro-2-hydroxyphenyl)methylidene]amino}pyrimidine-2,4(1H,3H)-dione
TL;DR: 5-{[(E)-(5-chloro-2-hydroxyphenyl)methylidene]amino}pyrimidine-2,4(1H,3H)-dione (CAS 273745-71-4) is a chemical compound with molecular formula C11H8ClN3O3 and molecular weight 265.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-[(5-chloro-2-hydroxyphenyl)methylideneamino]-1H-pyrimidine-2,4-dione
Also Known As: NCI60_041391, AE-848/34435040, (E)-5-((5-chloro-2-hydroxybenzylidene)amino)pyrimidine-2,4(1H,3H)-dione, 5-[(5-chloro-2-hydroxybenzylidene)amino]-2,4(1H,3H)-pyrimidinedione, 5-[(3-chloro-6-oxocyclohexa-2,4-dien-1-ylidene)methylamino]-1H-pyrimidine-2,4-dione
| Molecular Formula | C11H8ClN3O3 |
|---|---|
| Molecular Weight | 265.03 g/mol |
| LogP | 0.8 |
| Topological Polar Surface Area | 90.8 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 265.02542 |
| Heavy Atoms | 18 |
| Complexity | 422.0 |
Chemical Identifiers
| CAS Number | 273745-71-4 |
|---|---|
| SMILES | C1=CC(=C(C=C1Cl)C=NC2=CNC(=O)NC2=O)O |
| InChIKey | QGYSILWPKRLXKZ-UHFFFAOYSA-N |
Product Overview
5-{[(E)-(5-chloro-2-hydroxyphenyl)methylidene]amino}pyrimidine-2,4(1H,3H)-dione (CAS 273745-71-4), with molecular formula C11H8ClN3O3 and molecular weight 265.03 g/mol. IUPAC: 5-[(5-chloro-2-hydroxyphenyl)methylideneamino]-1H-pyrimidine-2,4-dione.
Chemical Property Profile of 5-{[(E)-(5-chloro-2-hydroxyphenyl)methylidene]amino}pyrimidine-2,4(1H,3H)-dione
Property Insights of 5-{[(E)-(5-chloro-2-hydroxyphenyl)methylidene]amino}pyrimidine-2,4(1H,3H)-dione
The XLogP value of 0.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-{[(E)-(5-chloro-2-hydroxyphenyl)methylidene]amino}pyrimidine-2,4(1H,3H)-dione. The TPSA of 90.8 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-{[(E)-(5-chloro-2-hydroxyphenyl)methylidene]amino}pyrimidine-2,4(1H,3H)-dione. Following Lipinski's Rule of Five, 5-{[(E)-(5-chloro-2-hydroxyphenyl)methylidene]amino}pyrimidine-2,4(1H,3H)-dione has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-{[(E)-(5-chloro-2-hydroxyphenyl)methylidene]amino}pyrimidine-2,4(1H,3H)-dione?
The CAS number of 5-{[(E)-(5-chloro-2-hydroxyphenyl)methylidene]amino}pyrimidine-2,4(1H,3H)-dione is 273745-71-4.
What is the molecular formula of 5-{[(E)-(5-chloro-2-hydroxyphenyl)methylidene]amino}pyrimidine-2,4(1H,3H)-dione?
The molecular formula of 5-{[(E)-(5-chloro-2-hydroxyphenyl)methylidene]amino}pyrimidine-2,4(1H,3H)-dione is C11H8ClN3O3.
What is the molecular weight of 5-{[(E)-(5-chloro-2-hydroxyphenyl)methylidene]amino}pyrimidine-2,4(1H,3H)-dione?
The molecular weight of 5-{[(E)-(5-chloro-2-hydroxyphenyl)methylidene]amino}pyrimidine-2,4(1H,3H)-dione is 265.03 g/mol.
Where can I buy 5-{[(E)-(5-chloro-2-hydroxyphenyl)methylidene]amino}pyrimidine-2,4(1H,3H)-dione?
You can request a quote for 5-{[(E)-(5-chloro-2-hydroxyphenyl)methylidene]amino}pyrimidine-2,4(1H,3H)-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-{[(E)-(5-chloro-2-hydroxyphenyl)methylidene]amino}pyrimidine-2,4(1H,3H)-dione?
Yes, KEHONG BIO provides custom synthesis services for 5-{[(E)-(5-chloro-2-hydroxyphenyl)methylidene]amino}pyrimidine-2,4(1H,3H)-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.