Niaprazine
TL;DR: Niaprazine (CAS 27367-90-4) is a chemical compound with molecular formula C20H25FN4O and molecular weight 356.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[4-[4-(4-fluorophenyl)piperazin-1-yl]butan-2-yl]pyridine-3-carboxamide
Also Known As: Niaprazine, Nopron, Niaprazina, Niaprazinum, Niaprazine, (+)-
| Molecular Formula | C20H25FN4O |
|---|---|
| Molecular Weight | 356.20 g/mol |
| LogP | 2.6 |
| Topological Polar Surface Area | 48.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 356.20123 |
| Heavy Atoms | 26 |
| Complexity | 434.0 |
Chemical Identifiers
| CAS Number | 27367-90-4 |
|---|---|
| SMILES | CC(CCN1CCN(CC1)C2=CC=C(C=C2)F)NC(=O)C3=CN=CC=C3 |
| InChIKey | RSKQGBFMNPDPLR-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 8 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Niaprazine (CAS 27367-90-4), with molecular formula C20H25FN4O and molecular weight 356.20 g/mol. IUPAC: N-[4-[4-(4-fluorophenyl)piperazin-1-yl]butan-2-yl]pyridine-3-carboxamide.
Chemical Property Profile of Niaprazine
Property Insights of Niaprazine
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Niaprazine. With a topological polar surface area (TPSA) of 48.5 Ų, Niaprazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Niaprazine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Niaprazine?
The CAS number of Niaprazine is 27367-90-4.
What is the molecular formula of Niaprazine?
The molecular formula of Niaprazine is C20H25FN4O.
What is the molecular weight of Niaprazine?
The molecular weight of Niaprazine is 356.20 g/mol.
Where can I buy Niaprazine?
You can request a quote for Niaprazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Niaprazine?
Yes, KEHONG BIO provides custom synthesis services for Niaprazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.