2-Cyanophenyl isothiocyanate structure

2-Cyanophenyl isothiocyanate

TL;DR: 2-Cyanophenyl isothiocyanate (CAS 273221-77-5) is a chemical compound with molecular formula C8H4N2S and molecular weight 160.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-isothiocyanatobenzonitrile

Also Known As: 2-Cyanophenyl isothiocyanate, 2-Isothiocyanatobenzonitrile, 2-Cyanophenylisothiocyanate, Phenyl carbamate, Benzonitrile,2-isothiocyanato-

CAS: 273221-77-5
Molecular Formula C8H4N2S
Molecular Weight 160.01 g/mol
LogP 3.0
Topological Polar Surface Area 68.2 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 3
Rotatable Bonds 1
Exact Mass 160.00952
Heavy Atoms 11
Complexity 221.0

Chemical Identifiers

CAS Number 273221-77-5
SMILES C1=CC=C(C(=C1)C#N)N=C=S
InChIKey GDHYPPBFBJXNRE-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (1 patents) Heterocyclic Building Blocks (24 patents) Pharmaceutical Intermediates (17 patents)

Product Overview

2-Cyanophenyl isothiocyanate (CAS 273221-77-5), with molecular formula C8H4N2S and molecular weight 160.01 g/mol. IUPAC: 2-isothiocyanatobenzonitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 2-Cyanophenyl isothiocyanate

XLogP
3.0
TPSA (Topological Polar Surface Area)
68.2
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
3
Rotatable Bonds
1
Heavy Atoms
11
Complexity
221.0
Exact Mass
160.00952
Monoisotopic Mass
160.00952
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2-Cyanophenyl isothiocyanate

The XLogP value of 3.0 indicates that 2-Cyanophenyl isothiocyanate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 68.2 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-Cyanophenyl isothiocyanate. Following Lipinski's Rule of Five, 2-Cyanophenyl isothiocyanate has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2-Cyanophenyl isothiocyanate?

The CAS number of 2-Cyanophenyl isothiocyanate is 273221-77-5.

What is the molecular formula of 2-Cyanophenyl isothiocyanate?

The molecular formula of 2-Cyanophenyl isothiocyanate is C8H4N2S.

What is the molecular weight of 2-Cyanophenyl isothiocyanate?

The molecular weight of 2-Cyanophenyl isothiocyanate is 160.01 g/mol.

Where can I buy 2-Cyanophenyl isothiocyanate?

You can request a quote for 2-Cyanophenyl isothiocyanate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2-Cyanophenyl isothiocyanate?

Yes, KEHONG BIO provides custom synthesis services for 2-Cyanophenyl isothiocyanate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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