Colchicine, N-deacetyl-10-thio-
TL;DR: Colchicine, N-deacetyl-10-thio- (CAS 2731-16-0) is a chemical compound with molecular formula C20H23NO4S and molecular weight 373.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(7S)-7-amino-1,2,3-trimethoxy-10-methylsulfanyl-6,7-dihydro-5H-benzo[a]heptalen-9-one
Also Known As: Thio-colciran, Thiolcolciran, N-Deacetylthiocolchicine, Thiocolciran, Deacetylthiocolchicine
| Molecular Formula | C20H23NO4S |
|---|---|
| Molecular Weight | 373.13 g/mol |
| LogP | 1.5 |
| Topological Polar Surface Area | 96.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 373.13477 |
| Heavy Atoms | 26 |
| Complexity | 642.0 |
Chemical Identifiers
| CAS Number | 2731-16-0 |
|---|---|
| SMILES | COC1=C(C(=C2C(=C1)CC[C@@H](C3=CC(=O)C(=CC=C32)SC)N)OC)OC |
| InChIKey | NUNCOHUMTCDISK-AWEZNQCLSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Colchicine, N-deacetyl-10-thio- (CAS 2731-16-0), with molecular formula C20H23NO4S and molecular weight 373.13 g/mol. IUPAC: (7S)-7-amino-1,2,3-trimethoxy-10-methylsulfanyl-6,7-dihydro-5H-benzo[a]heptalen-9-one.
Chemical Property Profile of Colchicine, N-deacetyl-10-thio-
Property Insights of Colchicine, N-deacetyl-10-thio-
The XLogP value of 1.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Colchicine, N-deacetyl-10-thio-. The TPSA of 96.1 Ų falls within the moderate polarity range, balancing permeability and solubility for Colchicine, N-deacetyl-10-thio-. Following Lipinski's Rule of Five, Colchicine, N-deacetyl-10-thio- has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Colchicine, N-deacetyl-10-thio-?
The CAS number of Colchicine, N-deacetyl-10-thio- is 2731-16-0.
What is the molecular formula of Colchicine, N-deacetyl-10-thio-?
The molecular formula of Colchicine, N-deacetyl-10-thio- is C20H23NO4S.
What is the molecular weight of Colchicine, N-deacetyl-10-thio-?
The molecular weight of Colchicine, N-deacetyl-10-thio- is 373.13 g/mol.
Where can I buy Colchicine, N-deacetyl-10-thio-?
You can request a quote for Colchicine, N-deacetyl-10-thio- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Colchicine, N-deacetyl-10-thio-?
Yes, KEHONG BIO provides custom synthesis services for Colchicine, N-deacetyl-10-thio- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.