Thiocolchicine
TL;DR: Thiocolchicine (CAS 2730-71-4) is a chemical compound with molecular formula C22H25NO5S and molecular weight 415.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(7S)-1,2,3-trimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Also Known As: Thiocolchicine, Thiocholchicine, Colchicine, 10-thio-, 10-Thio-colchicine, 10-Thiocolchicine
| Molecular Formula | C22H25NO5S |
|---|---|
| Molecular Weight | 415.15 g/mol |
| LogP | 1.8 |
| Topological Polar Surface Area | 99.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 415.14536 |
| Heavy Atoms | 29 |
| Complexity | 743.0 |
Chemical Identifiers
| CAS Number | 2730-71-4 |
|---|---|
| SMILES | CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)SC)OC)OC)OC |
| InChIKey | CMEGANPVAXDBPL-INIZCTEOSA-N |
Patent-Derived Application Labels
Derived from 9 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Thiocolchicine (CAS 2730-71-4), with molecular formula C22H25NO5S and molecular weight 415.15 g/mol. IUPAC: N-[(7S)-1,2,3-trimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide.
Chemical Property Profile of Thiocolchicine
Property Insights of Thiocolchicine
The XLogP value of 1.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Thiocolchicine. The TPSA of 99.2 Ų falls within the moderate polarity range, balancing permeability and solubility for Thiocolchicine. Following Lipinski's Rule of Five, Thiocolchicine has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Thiocolchicine?
The CAS number of Thiocolchicine is 2730-71-4.
What is the molecular formula of Thiocolchicine?
The molecular formula of Thiocolchicine is C22H25NO5S.
What is the molecular weight of Thiocolchicine?
The molecular weight of Thiocolchicine is 415.15 g/mol.
Where can I buy Thiocolchicine?
You can request a quote for Thiocolchicine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Thiocolchicine?
Yes, KEHONG BIO provides custom synthesis services for Thiocolchicine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.