(+)-Bupivacaine
TL;DR: (+)-Bupivacaine (CAS 27262-45-9) is a chemical compound with molecular formula C18H28N2O and molecular weight 288.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R)-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
Also Known As: (R)-bupivacaine, (+)-bupivacaine, D-bupivacaine, D-(+)-bupivacaine, DEXTROBUPIVACAINE
| Molecular Formula | C18H28N2O |
|---|---|
| Molecular Weight | 288.22 g/mol |
| LogP | 3.4 |
| Topological Polar Surface Area | 32.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 5 |
| Exact Mass | 288.22015 |
| Heavy Atoms | 21 |
| Complexity | 321.0 |
Chemical Identifiers
| CAS Number | 27262-45-9 |
|---|---|
| SMILES | CCCCN1CCCC[C@@H]1C(=O)NC2=C(C=CC=C2C)C |
| InChIKey | LEBVLXFERQHONN-MRXNPFEDSA-N |
Patent-Derived Application Labels
Derived from 10 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
(+)-Bupivacaine (CAS 27262-45-9), with molecular formula C18H28N2O and molecular weight 288.22 g/mol. IUPAC: (2R)-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide.
Chemical Property Profile of (+)-Bupivacaine
Property Insights of (+)-Bupivacaine
The XLogP value of 3.4 indicates that (+)-Bupivacaine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.3 Ų, (+)-Bupivacaine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (+)-Bupivacaine has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (+)-Bupivacaine?
The CAS number of (+)-Bupivacaine is 27262-45-9.
What is the molecular formula of (+)-Bupivacaine?
The molecular formula of (+)-Bupivacaine is C18H28N2O.
What is the molecular weight of (+)-Bupivacaine?
The molecular weight of (+)-Bupivacaine is 288.22 g/mol.
Where can I buy (+)-Bupivacaine?
You can request a quote for (+)-Bupivacaine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (+)-Bupivacaine?
Yes, KEHONG BIO provides custom synthesis services for (+)-Bupivacaine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.