Ketazolam
TL;DR: Ketazolam (CAS 27223-35-4) is a chemical compound with molecular formula C20H17ClN2O3 and molecular weight 368.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
11-chloro-2,8-dimethyl-12b-phenyl-6H-[1,3]oxazino[3,2-d][1,4]benzodiazepine-4,7-dione
Also Known As: KETAZOLAM, Unakalm, Ansieten, Anxon, Loftran
| Molecular Formula | C20H17ClN2O3 |
|---|---|
| Molecular Weight | 368.09 g/mol |
| LogP | 3.0 |
| Topological Polar Surface Area | 49.9 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 368.09277 |
| Heavy Atoms | 26 |
| Complexity | 631.0 |
| Melting Point | 174-176 |
| Solubility | 8.39e-02 g/L |
Chemical Identifiers
| CAS Number | 27223-35-4 |
|---|---|
| SMILES | CC1=CC(=O)N2CC(=O)N(C3=C(C2(O1)C4=CC=CC=C4)C=C(C=C3)Cl)C |
| InChIKey | PWAJCNITSBZRBL-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 10 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Ketazolam (CAS 27223-35-4), with molecular formula C20H17ClN2O3 and molecular weight 368.09 g/mol. IUPAC: 11-chloro-2,8-dimethyl-12b-phenyl-6H-[1,3]oxazino[3,2-d][1,4]benzodiazepine-4,7-dione.
Chemical Property Profile of Ketazolam
Property Insights of Ketazolam
The XLogP value of 3.0 indicates that Ketazolam is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.9 Ų, Ketazolam exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Ketazolam has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Ketazolam?
The CAS number of Ketazolam is 27223-35-4.
What is the molecular formula of Ketazolam?
The molecular formula of Ketazolam is C20H17ClN2O3.
What is the molecular weight of Ketazolam?
The molecular weight of Ketazolam is 368.09 g/mol.
Where can I buy Ketazolam?
You can request a quote for Ketazolam directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Ketazolam?
Yes, KEHONG BIO provides custom synthesis services for Ketazolam and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.