![N-[4-(hydroxymethyl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]-N-phenylpropanamide structure](/static/products/2713/27132-83-8.webp)
N-[4-(hydroxymethyl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]-N-phenylpropanamide
TL;DR: N-[4-(hydroxymethyl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]-N-phenylpropanamide (CAS 27132-83-8) is a chemical compound with molecular formula C21H28N2O2S and molecular weight 372.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[4-(hydroxymethyl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]-N-phenylpropanamide
Also Known As: Desmethylsufentanil, n-{4-(hydroxymethyl)-1-[2-(thiophen-3-yl)ethyl]piperidin-4-yl}-n-phenylpropanamide, N-[4-(hydroxymethyl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]-N-phenylpropanamide, N-(4-(Hydroxymethyl)-1-(2-(2-Thienyl)Ethyl)-4-Piperidinyl)-N-Phenylpro Panamide
| Molecular Formula | C21H28N2O2S |
|---|---|
| Molecular Weight | 372.19 g/mol |
| LogP | 3.1 |
| Topological Polar Surface Area | 72.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 7 |
| Exact Mass | 372.18716 |
| Heavy Atoms | 26 |
| Complexity | 445.0 |
Chemical Identifiers
| CAS Number | 27132-83-8 |
|---|---|
| SMILES | CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC3=CSC=C3)CO |
| InChIKey | PIJNARLBQANMKU-UHFFFAOYSA-N |
Product Overview
N-[4-(hydroxymethyl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]-N-phenylpropanamide (CAS 27132-83-8), with molecular formula C21H28N2O2S and molecular weight 372.19 g/mol. IUPAC: N-[4-(hydroxymethyl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]-N-phenylpropanamide.
Chemical Property Profile of N-[4-(hydroxymethyl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]-N-phenylpropanamide
Property Insights of N-[4-(hydroxymethyl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]-N-phenylpropanamide
The XLogP value of 3.1 indicates that N-[4-(hydroxymethyl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]-N-phenylpropanamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 72.0 Ų falls within the moderate polarity range, balancing permeability and solubility for N-[4-(hydroxymethyl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]-N-phenylpropanamide. Following Lipinski's Rule of Five, N-[4-(hydroxymethyl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]-N-phenylpropanamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-[4-(hydroxymethyl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]-N-phenylpropanamide?
The CAS number of N-[4-(hydroxymethyl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]-N-phenylpropanamide is 27132-83-8.
What is the molecular formula of N-[4-(hydroxymethyl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]-N-phenylpropanamide?
The molecular formula of N-[4-(hydroxymethyl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]-N-phenylpropanamide is C21H28N2O2S.
What is the molecular weight of N-[4-(hydroxymethyl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]-N-phenylpropanamide?
The molecular weight of N-[4-(hydroxymethyl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]-N-phenylpropanamide is 372.19 g/mol.
Where can I buy N-[4-(hydroxymethyl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]-N-phenylpropanamide?
You can request a quote for N-[4-(hydroxymethyl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]-N-phenylpropanamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-[4-(hydroxymethyl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]-N-phenylpropanamide?
Yes, KEHONG BIO provides custom synthesis services for N-[4-(hydroxymethyl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]-N-phenylpropanamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.