2,2,4-Trihydroxychalcone
TL;DR: 2,2,4-Trihydroxychalcone (CAS 26962-50-5) is a chemical compound with molecular formula C15H12O4 and molecular weight 256.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(2,4-dihydroxyphenyl)-3-(2-hydroxyphenyl)prop-2-en-1-one
Also Known As: 2,2,4-trihydroxychalcone, 2',4',2-Trihydroxychalcone, NCI60_012182, 1-(2,4-dihydroxyphenyl)-3-(2-hydroxyphenyl)prop-2-en-1-one, 2-Propen-1-one,1-(2,4-dihydroxyphenyl)-3-(2-hydroxyphenyl)-
| Molecular Formula | C15H12O4 |
|---|---|
| Molecular Weight | 256.07 g/mol |
| LogP | 3.2 |
| Topological Polar Surface Area | 77.8 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 256.07355 |
| Heavy Atoms | 19 |
| Complexity | 339.0 |
Chemical Identifiers
| CAS Number | 26962-50-5 |
|---|---|
| SMILES | C1=CC=C(C(=C1)C=CC(=O)C2=C(C=C(C=C2)O)O)O |
| InChIKey | MACMAADVRVVHBD-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
2,2,4-Trihydroxychalcone (CAS 26962-50-5), with molecular formula C15H12O4 and molecular weight 256.07 g/mol. IUPAC: 1-(2,4-dihydroxyphenyl)-3-(2-hydroxyphenyl)prop-2-en-1-one.
Chemical Property Profile of 2,2,4-Trihydroxychalcone
Property Insights of 2,2,4-Trihydroxychalcone
The XLogP value of 3.2 indicates that 2,2,4-Trihydroxychalcone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 77.8 Ų falls within the moderate polarity range, balancing permeability and solubility for 2,2,4-Trihydroxychalcone. Following Lipinski's Rule of Five, 2,2,4-Trihydroxychalcone has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2,2,4-Trihydroxychalcone?
The CAS number of 2,2,4-Trihydroxychalcone is 26962-50-5.
What is the molecular formula of 2,2,4-Trihydroxychalcone?
The molecular formula of 2,2,4-Trihydroxychalcone is C15H12O4.
What is the molecular weight of 2,2,4-Trihydroxychalcone?
The molecular weight of 2,2,4-Trihydroxychalcone is 256.07 g/mol.
Where can I buy 2,2,4-Trihydroxychalcone?
You can request a quote for 2,2,4-Trihydroxychalcone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2,2,4-Trihydroxychalcone?
Yes, KEHONG BIO provides custom synthesis services for 2,2,4-Trihydroxychalcone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.