3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione
TL;DR: 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione (CAS 26581-81-7) is a chemical compound with molecular formula C13H12N2O3 and molecular weight 244.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione
Also Known As: Phthalimidinoglutarimide, Thalidomide Impurity 1, 2-(2,6-dioxopiperidin-3-yl)phthalimidine, em12, starbld0036086
| Molecular Formula | C13H12N2O3 |
|---|---|
| Molecular Weight | 244.08 g/mol |
| LogP | 0.2 |
| Topological Polar Surface Area | 66.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 244.0848 |
| Heavy Atoms | 18 |
| Complexity | 407.0 |
| Melting Point | 460 to 240.0 °C |
| Solubility | less than 1 mg/mL at 72 °F (NTP, 1992) |
Chemical Identifiers
| CAS Number | 26581-81-7 |
|---|---|
| SMILES | C1CC(=O)NC(=O)C1N2CC3=CC=CC=C3C2=O |
| InChIKey | WENKGSGGXGQHSH-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 7 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione (CAS 26581-81-7), with molecular formula C13H12N2O3 and molecular weight 244.08 g/mol. IUPAC: 3-(3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione.
Chemical Property Profile of 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione
Property Insights of 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione
The XLogP value of 0.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione. The TPSA of 66.5 Ų falls within the moderate polarity range, balancing permeability and solubility for 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione. Following Lipinski's Rule of Five, 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione?
The CAS number of 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione is 26581-81-7.
What is the molecular formula of 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione?
The molecular formula of 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione is C13H12N2O3.
What is the molecular weight of 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione?
The molecular weight of 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione is 244.08 g/mol.
Where can I buy 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione?
You can request a quote for 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione?
Yes, KEHONG BIO provides custom synthesis services for 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.