Ro 41-2175
TL;DR: Ro 41-2175 (CAS 26495-19-2) is a chemical compound with molecular formula C14H12ClF4N3O4S and molecular weight 429.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)pyrimidin-1-yl]phenyl]-N-methylmethanesulfonamide
Also Known As: Ro 41-2175, Ro-41-2175, Methanesulfonamide, N-(2-chloro-5-(3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1(2H)-pyrimidinyl)-4-fluorophenyl)-N-methyl-, n-{2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-3,6-dihydropyrimidin-1(2h)-yl]phenyl}-n-methylmethanesulfonamide, N-[2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)pyrimidin-1-yl]phenyl]-N-methylmethanesulfonamide
| Molecular Formula | C14H12ClF4N3O4S |
|---|---|
| Molecular Weight | 429.02 g/mol |
| LogP | 1.7 |
| Topological Polar Surface Area | 86.4 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 3 |
| Exact Mass | 429.0173 |
| Heavy Atoms | 27 |
| Complexity | 767.0 |
Chemical Identifiers
| CAS Number | 26495-19-2 |
|---|---|
| SMILES | CN1C(=CC(=O)N(C1=O)C2=CC(=C(C=C2F)Cl)N(C)S(=O)(=O)C)C(F)(F)F |
| InChIKey | CWJQXFJBKHLCOM-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Ro 41-2175 (CAS 26495-19-2), with molecular formula C14H12ClF4N3O4S and molecular weight 429.02 g/mol. IUPAC: N-[2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)pyrimidin-1-yl]phenyl]-N-methylmethanesulfonamide.
Chemical Property Profile of Ro 41-2175
Property Insights of Ro 41-2175
The XLogP value of 1.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Ro 41-2175. The TPSA of 86.4 Ų falls within the moderate polarity range, balancing permeability and solubility for Ro 41-2175. Following Lipinski's Rule of Five, Ro 41-2175 has 0 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Ro 41-2175?
The CAS number of Ro 41-2175 is 26495-19-2.
What is the molecular formula of Ro 41-2175?
The molecular formula of Ro 41-2175 is C14H12ClF4N3O4S.
What is the molecular weight of Ro 41-2175?
The molecular weight of Ro 41-2175 is 429.02 g/mol.
Where can I buy Ro 41-2175?
You can request a quote for Ro 41-2175 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Ro 41-2175?
Yes, KEHONG BIO provides custom synthesis services for Ro 41-2175 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.