pregnanediol structure

pregnanediol

TL;DR: pregnanediol (CAS 26445-07-8) is a chemical compound with molecular formula C21H36O2 and molecular weight 320.27 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(8S,9S,10S,13R,14S,17S)-17-ethyl-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,3-diol

Also Known As: pregnanediol, Pregnane-3,3-diol, Pregnanediol (VAN), (8S,9S,10S,13R,14S,17S)-17-ethyl-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,3-diol

CAS: 26445-07-8
Molecular Formula C21H36O2
Molecular Weight 320.27 g/mol
LogP 4.7362
Topological Polar Surface Area 40.46 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 2
Rotatable Bonds 1
Exact Mass 320.27155
Heavy Atoms 23
Complexity 472.46204

Chemical Identifiers

CAS Number 26445-07-8
SMILES CC[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4[C@@]3(CCC(C4)(O)O)C)C

Product Overview

pregnanediol (CAS 26445-07-8), with molecular formula C21H36O2 and molecular weight 320.27 g/mol. IUPAC: (8S,9S,10S,13R,14S,17S)-17-ethyl-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,3-diol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of pregnanediol

XLogP
4.7362
TPSA (Topological Polar Surface Area)
40.46
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
2
Rotatable Bonds
1
Heavy Atoms
23
Complexity
472.46204
Exact Mass
320.27155
Monoisotopic Mass
320.27155
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of pregnanediol

The XLogP value of 4.7362 indicates that pregnanediol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.46 Ų, pregnanediol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, pregnanediol has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of pregnanediol?

The CAS number of pregnanediol is 26445-07-8.

What is the molecular formula of pregnanediol?

The molecular formula of pregnanediol is C21H36O2.

What is the molecular weight of pregnanediol?

The molecular weight of pregnanediol is 320.27 g/mol.

Where can I buy pregnanediol?

You can request a quote for pregnanediol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for pregnanediol?

Yes, KEHONG BIO provides custom synthesis services for pregnanediol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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