N-(2-chloropyridin-3-yl)-4-(trifluoromethoxy)benzenesulfonamide
TL;DR: N-(2-chloropyridin-3-yl)-4-(trifluoromethoxy)benzenesulfonamide (CAS 263387-20-8) is a chemical compound with molecular formula C12H8ClF3N2O3S and molecular weight 351.99 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(2-chloro-3-pyridinyl)-4-(trifluoromethoxy)benzenesulfonamide
Also Known As: N-(2-chloropyridin-3-yl)-4-(trifluoromethoxy)benzenesulfonamide, N1-(2-chloro-3-pyridyl)-4-(trifluoromethoxy)benzene-1-sulphonamide, N-(2-Chloro-3-pyridinyl)-4-(trifluoromethoxy)benzenesulfonamide, N1-(2-chloro-3-pyridyl)-4-(trifluoromethoxy)benzene-1-sulfonamide
| Molecular Formula | C12H8ClF3N2O3S |
|---|---|
| Molecular Weight | 351.99 g/mol |
| LogP | 3.4344 |
| Topological Polar Surface Area | 68.29 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 351.98962 |
| Heavy Atoms | 22 |
| Complexity | 763.9311 |
Chemical Identifiers
| CAS Number | 263387-20-8 |
|---|---|
| SMILES | C1=CC(=C(N=C1)Cl)NS(=O)(=O)C2=CC=C(C=C2)OC(F)(F)F |
Product Overview
N-(2-chloropyridin-3-yl)-4-(trifluoromethoxy)benzenesulfonamide (CAS 263387-20-8), with molecular formula C12H8ClF3N2O3S and molecular weight 351.99 g/mol. IUPAC: N-(2-chloro-3-pyridinyl)-4-(trifluoromethoxy)benzenesulfonamide.
Chemical Property Profile of N-(2-chloropyridin-3-yl)-4-(trifluoromethoxy)benzenesulfonamide
Property Insights of N-(2-chloropyridin-3-yl)-4-(trifluoromethoxy)benzenesulfonamide
The XLogP value of 3.4344 indicates that N-(2-chloropyridin-3-yl)-4-(trifluoromethoxy)benzenesulfonamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 68.29 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(2-chloropyridin-3-yl)-4-(trifluoromethoxy)benzenesulfonamide. Following Lipinski's Rule of Five, N-(2-chloropyridin-3-yl)-4-(trifluoromethoxy)benzenesulfonamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(2-chloropyridin-3-yl)-4-(trifluoromethoxy)benzenesulfonamide?
The CAS number of N-(2-chloropyridin-3-yl)-4-(trifluoromethoxy)benzenesulfonamide is 263387-20-8.
What is the molecular formula of N-(2-chloropyridin-3-yl)-4-(trifluoromethoxy)benzenesulfonamide?
The molecular formula of N-(2-chloropyridin-3-yl)-4-(trifluoromethoxy)benzenesulfonamide is C12H8ClF3N2O3S.
What is the molecular weight of N-(2-chloropyridin-3-yl)-4-(trifluoromethoxy)benzenesulfonamide?
The molecular weight of N-(2-chloropyridin-3-yl)-4-(trifluoromethoxy)benzenesulfonamide is 351.99 g/mol.
Where can I buy N-(2-chloropyridin-3-yl)-4-(trifluoromethoxy)benzenesulfonamide?
You can request a quote for N-(2-chloropyridin-3-yl)-4-(trifluoromethoxy)benzenesulfonamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(2-chloropyridin-3-yl)-4-(trifluoromethoxy)benzenesulfonamide?
Yes, KEHONG BIO provides custom synthesis services for N-(2-chloropyridin-3-yl)-4-(trifluoromethoxy)benzenesulfonamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.