4-(Chlorodifluoromethyl)-6-methylpyrimidin-2-amine
TL;DR: 4-(Chlorodifluoromethyl)-6-methylpyrimidin-2-amine (CAS 263276-46-6) is a chemical compound with molecular formula C6H6ClF2N3 and molecular weight 193.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[chloro(difluoro)methyl]-6-methylpyrimidin-2-amine
Also Known As: 4-(chlorodifluoromethyl)-6-methylpyrimidin-2-amine, 4-[chloro(difluoro)methyl]-6-methylpyrimidin-2-amine, 4-(Chloro(difluoro)methyl)-6-methyl-2-pyrimidinamine, 4-[chloro(difluoro)methyl]-6-methyl-2-pyrimidinylamine, 2-Pyrimidinamine, 4-(chlorodifluoromethyl)-6-methyl-
| Molecular Formula | C6H6ClF2N3 |
|---|---|
| Molecular Weight | 193.02 g/mol |
| LogP | 1.65532 |
| Topological Polar Surface Area | 51.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 193.02184 |
| Heavy Atoms | 12 |
| Complexity | 277.08493 |
Chemical Identifiers
| CAS Number | 263276-46-6 |
|---|---|
| SMILES | CC1=CC(=NC(=N1)N)C(F)(F)Cl |
Product Overview
4-(Chlorodifluoromethyl)-6-methylpyrimidin-2-amine (CAS 263276-46-6), with molecular formula C6H6ClF2N3 and molecular weight 193.02 g/mol. IUPAC: 4-[chloro(difluoro)methyl]-6-methylpyrimidin-2-amine.
Chemical Property Profile of 4-(Chlorodifluoromethyl)-6-methylpyrimidin-2-amine
Property Insights of 4-(Chlorodifluoromethyl)-6-methylpyrimidin-2-amine
The XLogP value of 1.65532 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-(Chlorodifluoromethyl)-6-methylpyrimidin-2-amine. With a topological polar surface area (TPSA) of 51.8 Ų, 4-(Chlorodifluoromethyl)-6-methylpyrimidin-2-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(Chlorodifluoromethyl)-6-methylpyrimidin-2-amine has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(Chlorodifluoromethyl)-6-methylpyrimidin-2-amine?
The CAS number of 4-(Chlorodifluoromethyl)-6-methylpyrimidin-2-amine is 263276-46-6.
What is the molecular formula of 4-(Chlorodifluoromethyl)-6-methylpyrimidin-2-amine?
The molecular formula of 4-(Chlorodifluoromethyl)-6-methylpyrimidin-2-amine is C6H6ClF2N3.
What is the molecular weight of 4-(Chlorodifluoromethyl)-6-methylpyrimidin-2-amine?
The molecular weight of 4-(Chlorodifluoromethyl)-6-methylpyrimidin-2-amine is 193.02 g/mol.
Where can I buy 4-(Chlorodifluoromethyl)-6-methylpyrimidin-2-amine?
You can request a quote for 4-(Chlorodifluoromethyl)-6-methylpyrimidin-2-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(Chlorodifluoromethyl)-6-methylpyrimidin-2-amine?
Yes, KEHONG BIO provides custom synthesis services for 4-(Chlorodifluoromethyl)-6-methylpyrimidin-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.