1-amino-4-chloro-3H-indol-2-one
TL;DR: 1-amino-4-chloro-3H-indol-2-one (CAS 26221-73-8) is a chemical compound with molecular formula C8H7ClN2O and molecular weight 182.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-amino-4-chloro-3H-indol-2-one
Also Known As: 1-amino-4-chloro-3H-indol-2-one, NCIOpen2_000395, 1-amino-4-chloro-1,3-dihydro-2h-indol-2-one, 1-amino-4-chloro-1,3-dihydro-indol-2-one, 2H-Indol-2-one,1-amino-4-chloro-1,3-dihydro-
| Molecular Formula | C8H7ClN2O |
|---|---|
| Molecular Weight | 182.02 g/mol |
| LogP | 0.8 |
| Topological Polar Surface Area | 46.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 182.02469 |
| Heavy Atoms | 12 |
| Complexity | 209.0 |
Chemical Identifiers
| CAS Number | 26221-73-8 |
|---|---|
| SMILES | C1C2=C(C=CC=C2Cl)N(C1=O)N |
| InChIKey | KECLJHOOLBYOLO-UHFFFAOYSA-N |
Product Overview
1-amino-4-chloro-3H-indol-2-one (CAS 26221-73-8), with molecular formula C8H7ClN2O and molecular weight 182.02 g/mol. IUPAC: 1-amino-4-chloro-3H-indol-2-one.
Chemical Property Profile of 1-amino-4-chloro-3H-indol-2-one
Property Insights of 1-amino-4-chloro-3H-indol-2-one
The XLogP value of 0.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-amino-4-chloro-3H-indol-2-one. With a topological polar surface area (TPSA) of 46.3 Ų, 1-amino-4-chloro-3H-indol-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-amino-4-chloro-3H-indol-2-one has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-amino-4-chloro-3H-indol-2-one?
The CAS number of 1-amino-4-chloro-3H-indol-2-one is 26221-73-8.
What is the molecular formula of 1-amino-4-chloro-3H-indol-2-one?
The molecular formula of 1-amino-4-chloro-3H-indol-2-one is C8H7ClN2O.
What is the molecular weight of 1-amino-4-chloro-3H-indol-2-one?
The molecular weight of 1-amino-4-chloro-3H-indol-2-one is 182.02 g/mol.
Where can I buy 1-amino-4-chloro-3H-indol-2-one?
You can request a quote for 1-amino-4-chloro-3H-indol-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-amino-4-chloro-3H-indol-2-one?
Yes, KEHONG BIO provides custom synthesis services for 1-amino-4-chloro-3H-indol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.