Colchicine, 17,17,17-trifluoro-
TL;DR: Colchicine, 17,17,17-trifluoro- (CAS 26195-65-3) is a chemical compound with molecular formula C22H22F3NO6 and molecular weight 453.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2,2,2-trifluoro-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Also Known As: Colchicine analog, N-Trifluoroacetyl Deacetylcolchicine, Colchicine Impurity 25, COLCHICINE, 17,17,17-TRIFLUORO-, 17,17,17-Trifluorocolchicine
| Molecular Formula | C22H22F3NO6 |
|---|---|
| Molecular Weight | 453.14 g/mol |
| LogP | 1.7 |
| Topological Polar Surface Area | 83.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 5 |
| Exact Mass | 453.13992 |
| Heavy Atoms | 32 |
| Complexity | 834.0 |
Chemical Identifiers
| CAS Number | 26195-65-3 |
|---|---|
| SMILES | COC1=CC=C2C(=CC1=O)[C@H](CCC3=CC(=C(C(=C32)OC)OC)OC)NC(=O)C(F)(F)F |
| InChIKey | MCHADYPYCJQLMV-AWEZNQCLSA-N |
Product Overview
Colchicine, 17,17,17-trifluoro- (CAS 26195-65-3), with molecular formula C22H22F3NO6 and molecular weight 453.14 g/mol. IUPAC: 2,2,2-trifluoro-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide.
Chemical Property Profile of Colchicine, 17,17,17-trifluoro-
Property Insights of Colchicine, 17,17,17-trifluoro-
The XLogP value of 1.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Colchicine, 17,17,17-trifluoro-. The TPSA of 83.1 Ų falls within the moderate polarity range, balancing permeability and solubility for Colchicine, 17,17,17-trifluoro-. Following Lipinski's Rule of Five, Colchicine, 17,17,17-trifluoro- has 1 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Colchicine, 17,17,17-trifluoro-?
The CAS number of Colchicine, 17,17,17-trifluoro- is 26195-65-3.
What is the molecular formula of Colchicine, 17,17,17-trifluoro-?
The molecular formula of Colchicine, 17,17,17-trifluoro- is C22H22F3NO6.
What is the molecular weight of Colchicine, 17,17,17-trifluoro-?
The molecular weight of Colchicine, 17,17,17-trifluoro- is 453.14 g/mol.
Where can I buy Colchicine, 17,17,17-trifluoro-?
You can request a quote for Colchicine, 17,17,17-trifluoro- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Colchicine, 17,17,17-trifluoro-?
Yes, KEHONG BIO provides custom synthesis services for Colchicine, 17,17,17-trifluoro- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.