4,5-Difluoro-2-(trifluoromethyl)benzamide
TL;DR: 4,5-Difluoro-2-(trifluoromethyl)benzamide (CAS 261944-97-2) is a chemical compound with molecular formula C8H4F5NO and molecular weight 225.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4,5-difluoro-2-(trifluoromethyl)benzamide
Also Known As: 4,5-difluoro-2-(trifluoromethyl)benzamide, 2277AB, Benzamide, 4,5-difluoro-2-(trifluoromethyl)-
| Molecular Formula | C8H4F5NO |
|---|---|
| Molecular Weight | 225.02 g/mol |
| LogP | 2.0825 |
| Topological Polar Surface Area | 43.09 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 225.0213 |
| Heavy Atoms | 15 |
| Complexity | 412.22842 |
Chemical Identifiers
| CAS Number | 261944-97-2 |
|---|---|
| SMILES | C1=C(C(=CC(=C1F)F)C(F)(F)F)C(=O)N |
Product Overview
4,5-Difluoro-2-(trifluoromethyl)benzamide (CAS 261944-97-2), with molecular formula C8H4F5NO and molecular weight 225.02 g/mol. IUPAC: 4,5-difluoro-2-(trifluoromethyl)benzamide.
Chemical Property Profile of 4,5-Difluoro-2-(trifluoromethyl)benzamide
Property Insights of 4,5-Difluoro-2-(trifluoromethyl)benzamide
The XLogP value of 2.0825 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4,5-Difluoro-2-(trifluoromethyl)benzamide. With a topological polar surface area (TPSA) of 43.09 Ų, 4,5-Difluoro-2-(trifluoromethyl)benzamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4,5-Difluoro-2-(trifluoromethyl)benzamide has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4,5-Difluoro-2-(trifluoromethyl)benzamide?
The CAS number of 4,5-Difluoro-2-(trifluoromethyl)benzamide is 261944-97-2.
What is the molecular formula of 4,5-Difluoro-2-(trifluoromethyl)benzamide?
The molecular formula of 4,5-Difluoro-2-(trifluoromethyl)benzamide is C8H4F5NO.
What is the molecular weight of 4,5-Difluoro-2-(trifluoromethyl)benzamide?
The molecular weight of 4,5-Difluoro-2-(trifluoromethyl)benzamide is 225.02 g/mol.
Where can I buy 4,5-Difluoro-2-(trifluoromethyl)benzamide?
You can request a quote for 4,5-Difluoro-2-(trifluoromethyl)benzamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4,5-Difluoro-2-(trifluoromethyl)benzamide?
Yes, KEHONG BIO provides custom synthesis services for 4,5-Difluoro-2-(trifluoromethyl)benzamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.