![2-Methyl-1-{4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}propan-1-one structure](/static/products/2603/260367-81-5.webp)
2-Methyl-1-{4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}propan-1-one
TL;DR: 2-Methyl-1-{4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}propan-1-one (CAS 260367-81-5) is a chemical compound with molecular formula C14H18F3N3O and molecular weight 301.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-methyl-1-[4-[3-(trifluoromethyl)-2-pyridinyl]piperazin-1-yl]propan-1-one
Also Known As: 2-methyl-1-{4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}propan-1-one, 2-methyl-1-[4-[3-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]propan-1-one, 2-methyl-1-{4-[3-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}propan-1-one
| Molecular Formula | C14H18F3N3O |
|---|---|
| Molecular Weight | 301.14 g/mol |
| LogP | 2.405 |
| Topological Polar Surface Area | 36.44 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 301.1402 |
| Heavy Atoms | 21 |
| Complexity | 508.43085 |
Chemical Identifiers
| CAS Number | 260367-81-5 |
|---|---|
| SMILES | CC(C)C(=O)N1CCN(CC1)C2=C(C=CC=N2)C(F)(F)F |
Product Overview
2-Methyl-1-{4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}propan-1-one (CAS 260367-81-5), with molecular formula C14H18F3N3O and molecular weight 301.14 g/mol. IUPAC: 2-methyl-1-[4-[3-(trifluoromethyl)-2-pyridinyl]piperazin-1-yl]propan-1-one.
Chemical Property Profile of 2-Methyl-1-{4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}propan-1-one
Property Insights of 2-Methyl-1-{4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}propan-1-one
The XLogP value of 2.405 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-Methyl-1-{4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}propan-1-one. With a topological polar surface area (TPSA) of 36.44 Ų, 2-Methyl-1-{4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}propan-1-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Methyl-1-{4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}propan-1-one has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Methyl-1-{4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}propan-1-one?
The CAS number of 2-Methyl-1-{4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}propan-1-one is 260367-81-5.
What is the molecular formula of 2-Methyl-1-{4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}propan-1-one?
The molecular formula of 2-Methyl-1-{4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}propan-1-one is C14H18F3N3O.
What is the molecular weight of 2-Methyl-1-{4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}propan-1-one?
The molecular weight of 2-Methyl-1-{4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}propan-1-one is 301.14 g/mol.
Where can I buy 2-Methyl-1-{4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}propan-1-one?
You can request a quote for 2-Methyl-1-{4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}propan-1-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Methyl-1-{4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}propan-1-one?
Yes, KEHONG BIO provides custom synthesis services for 2-Methyl-1-{4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}propan-1-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.