(R)-Desmethylsibutramine hydrochloride
TL;DR: (R)-Desmethylsibutramine hydrochloride (CAS 259731-40-3) is a chemical compound with molecular formula C16H25Cl2N and molecular weight 301.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1R)-1-[1-(4-chlorophenyl)cyclobutyl]-N,3-dimethylbutan-1-amine;hydrochloride
Also Known As: (R)-Desmethylsibutramine hydrochloride, (R)-(+)-Desmethylsibutramine hcl, Desmethylsibutramine hydrochloride, (R)-, Desmethylsibutramine hydrochloride, (+)-, (R)-Desmethyl Sibutramine Hydrochloride
| Molecular Formula | C16H25Cl2N |
|---|---|
| Molecular Weight | 301.14 g/mol |
| LogP | 4.8176 |
| Topological Polar Surface Area | 12.03 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 5 |
| Exact Mass | 301.1364 |
| Heavy Atoms | 19 |
| Complexity | 382.24033 |
Chemical Identifiers
| CAS Number | 259731-40-3 |
|---|---|
| SMILES | CC(C)C[C@H](C1(CCC1)C2=CC=C(C=C2)Cl)NC.Cl |
Product Overview
(R)-Desmethylsibutramine hydrochloride (CAS 259731-40-3), with molecular formula C16H25Cl2N and molecular weight 301.14 g/mol. IUPAC: (1R)-1-[1-(4-chlorophenyl)cyclobutyl]-N,3-dimethylbutan-1-amine;hydrochloride.
Chemical Property Profile of (R)-Desmethylsibutramine hydrochloride
Property Insights of (R)-Desmethylsibutramine hydrochloride
The XLogP value of 4.8176 indicates that (R)-Desmethylsibutramine hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.03 Ų, (R)-Desmethylsibutramine hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (R)-Desmethylsibutramine hydrochloride has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (R)-Desmethylsibutramine hydrochloride?
The CAS number of (R)-Desmethylsibutramine hydrochloride is 259731-40-3.
What is the molecular formula of (R)-Desmethylsibutramine hydrochloride?
The molecular formula of (R)-Desmethylsibutramine hydrochloride is C16H25Cl2N.
What is the molecular weight of (R)-Desmethylsibutramine hydrochloride?
The molecular weight of (R)-Desmethylsibutramine hydrochloride is 301.14 g/mol.
Where can I buy (R)-Desmethylsibutramine hydrochloride?
You can request a quote for (R)-Desmethylsibutramine hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (R)-Desmethylsibutramine hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for (R)-Desmethylsibutramine hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.