Tmc-86B structure

Tmc-86B

TL;DR: Tmc-86B (CAS 259535-32-5) is a chemical compound with molecular formula C20H34N2O7 and molecular weight 414.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

6-hydroxy-N-[(2S)-3-hydroxy-1-[[1-[2-(hydroxymethyl)oxiran-2-yl]-4-methyl-1-oxopent-4-en-2-yl]amino]-1-oxopropan-2-yl]-6-methylheptanamide

Also Known As: TMC-86B, TMC 86B, TMC-86 B, J1.257.720F, 6-hydroxy-N-[(2S)-3-hydroxy-1-({1-[2-(hydroxymethyl)oxiran-2-yl]-4-methyl-1-oxopent-4-en-2-yl}amino)-1-oxopropan-2-yl]-6-methylheptanamide

CAS: 259535-32-5
Molecular Formula C20H34N2O7
Molecular Weight 414.24 g/mol
LogP -0.4238
Topological Polar Surface Area 148.49 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 7
Rotatable Bonds 14
Exact Mass 414.2366
Heavy Atoms 29
Complexity 608.4412

Chemical Identifiers

CAS Number 259535-32-5
SMILES CC(=C)CC(C(=O)C1(CO1)CO)NC(=O)[C@H](CO)NC(=O)CCCCC(C)(C)O

Product Overview

Tmc-86B (CAS 259535-32-5), with molecular formula C20H34N2O7 and molecular weight 414.24 g/mol. IUPAC: 6-hydroxy-N-[(2S)-3-hydroxy-1-[[1-[2-(hydroxymethyl)oxiran-2-yl]-4-methyl-1-oxopent-4-en-2-yl]amino]-1-oxopropan-2-yl]-6-methylheptanamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Tmc-86B

XLogP
-0.4238
TPSA (Topological Polar Surface Area)
148.49
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
7
Rotatable Bonds
14
Heavy Atoms
29
Complexity
608.4412
Exact Mass
414.2366
Monoisotopic Mass
414.2366
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Tmc-86B

The XLogP value of -0.4238 indicates that Tmc-86B is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 148.49 Ų indicates high polarity, suggesting Tmc-86B may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Tmc-86B has 5 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Tmc-86B?

The CAS number of Tmc-86B is 259535-32-5.

What is the molecular formula of Tmc-86B?

The molecular formula of Tmc-86B is C20H34N2O7.

What is the molecular weight of Tmc-86B?

The molecular weight of Tmc-86B is 414.24 g/mol.

Where can I buy Tmc-86B?

You can request a quote for Tmc-86B directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Tmc-86B?

Yes, KEHONG BIO provides custom synthesis services for Tmc-86B and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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